Cargando…

Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury

5-Fluorouracil (5-FU), irinotecan (CPT-11), oxaliplatin (L-OHP), and calcium folinate (CF) are widely used chemotherapeutic drugs to treat colorectal cancer. However, chemotherapeutic use is often accompanied by intestinal inflammation and gut microbiota disorder. Changes in gut microbiota may destr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Bin, Gui, Mengxuan, Ni, Zhuona, He, Yanbin, Zhao, Jinyan, Peng, Jun, Lin, Jiumao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769542/ https://www.ncbi.nlm.nih.gov/pubmed/36222691 http://dx.doi.org/10.1128/spectrum.01677-22

Ejemplares similares

RIP2 filament formation is required for NOD2 dependent NF-κB signalling
por: Pellegrini, Erika, et al.
Publicado: (2018)

The Inositol Phosphatase SHIP-1 Inhibits NOD2-Induced NF-κB Activation by Disturbing the Interaction of XIAP with RIP2
por: Condé, Claude, et al.
Publicado: (2012)

Differences in the Expression of TLR-2, NOD2, and NF-κB in Placenta Between Twins
por: Szylberg, Łukasz, et al.
Publicado: (2018)

Evaluation of different mucosal microbiota leads to gut microbiota-based prediction of type 1 diabetes in NOD mice
por: Hu, Youjia, et al.
Publicado: (2018)

The Tandem CARDs of NOD2: Intramolecular Interactions and Recognition of RIP2
por: Fridh, Veronica, et al.
Publicado: (2012)

GPC2 deficiency inhibits cell growth and metastasis in colon adenocarcinoma
por: Lin, Lumin, et al.
Publicado: (2022)

NOD1/NOD2 and RIP2 Regulate Endoplasmic Reticulum Stress-Induced Inflammation during Chlamydia Infection
por: Pham, Oanh H., et al.
Publicado: (2020)

NEMO Inhibits Programmed Necrosis in an NFκB-Independent Manner by Restraining RIP1
por: O’Donnell, Marie Anne, et al.
Publicado: (2012)

NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP
por: Kreuz, Sebastian, et al.
Publicado: (2004)

Regulation of temozolomide resistance in glioma cells via the RIP2/NF‐κB/MGMT pathway
por: Hu, Yu‐Hua, et al.
Publicado: (2021)

The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats
por: Liu, Feng-Yi, et al.
Publicado: (2020)

Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways
por: Shang, Haixia, et al.
Publicado: (2019)

ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis
por: Huang, Bin, et al.
Publicado: (2023)

Effect of Sulforaphane on NOD2 via NF-κB: implications for Crohn’s disease
por: Folkard, Danielle L, et al.
Publicado: (2015)

NF-κB is weakly activated in the NOD mouse model of type 1 diabetes
por: Irvin, Allison E., et al.
Publicado: (2018)

Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB
por: Chou, Tsui-Wen, et al.
Publicado: (2021)

Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis
por: Chen, Zhong, et al.
Publicado: (2020)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner
por: Kramer, Marcel, et al.
Publicado: (2010)

Involvement of ayu NOD2 in NF-κB and MAPK signaling pathways: Insights into functional conservation of NOD2 in antibacterial innate immunity
por: Ren, Yi, et al.
Publicado: (2018)

Gut Microbiota-Derived Diaminopimelic Acid Promotes the NOD1/RIP2 Signaling Pathway and Plays a Key Role in the Progression of Severe Acute Pancreatitis
por: Jiao, Juying, et al.
Publicado: (2022)

NF-κB-mediated degradation of the co-activator RIP140 regulates inflammatory response and contributes to endotoxin tolerance
por: Ho, Ping-Chih, et al.
Publicado: (2012)

RIP140-Mediated NF-κB Inflammatory Pathway Promotes Metabolic Dysregulation in Retinal Pigment Epithelium Cells
por: Guo, Zeli, et al.
Publicado: (2022)

Recognition of Lipopolysaccharide and Activation of NF-κB by Cytosolic Sensor NOD1 in Teleost Fish
por: Bi, Dekun, et al.
Publicado: (2018)

LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation
por: Yan, Ruiqing, et al.
Publicado: (2016)

The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex
por: Panda, Swarupa, et al.
Publicado: (2018)

Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
por: Samuel, Temesgen, et al.
Publicado: (2014)

Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells
por: Shi, Xiaoyu, et al.
Publicado: (2023)

Cigarette smoking induces the activation of RIP2/caspase-12/NF-κB axis in oral squamous cell carcinoma
por: Qian, Yajie, et al.
Publicado: (2022)

IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway
por: Chan, Leong-Perng, et al.
Publicado: (2016)

NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations
por: Le, Yi, et al.
Publicado: (2022)

GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors
por: Fukazawa, Atsuko, et al.
Publicado: (2008)

IKKα Contributes to Canonical NF-κB Activation Downstream of Nod1-Mediated Peptidoglycan Recognition
por: Kim, Man Lyang, et al.
Publicado: (2010)

NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis
por: Pandey, Amit K., et al.
Publicado: (2009)

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
por: Vlantis, Katerina, et al.
Publicado: (2016)

The API2-MALT1 Fusion Exploits TNFR Pathway-associated RIP1 Ubiquitination to Promote Oncogenic NF-κB Signaling
por: Rosebeck, Shaun, et al.
Publicado: (2013)

RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway
por: Li, Cheng-Zong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kgp02n0m4d0bnrsfth5582ocvc