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Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds
With the pressing antibiotic resistance pandemic, antivirulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive target for small molecules for antivirulence purposes. The...
Autores principales: | Dye, Keane J., Vogelaar, Nancy J., O’Hara, Megan, Sobrado, Pablo, Santos, Webster, Carlier, Paul R., Yang, Zhaomin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769694/ https://www.ncbi.nlm.nih.gov/pubmed/36377931 http://dx.doi.org/10.1128/spectrum.03877-22 |
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