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Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds

With the pressing antibiotic resistance pandemic, antivirulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive target for small molecules for antivirulence purposes. The...

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Detalles Bibliográficos
Autores principales:	Dye, Keane J., Vogelaar, Nancy J., O’Hara, Megan, Sobrado, Pablo, Santos, Webster, Carlier, Paul R., Yang, Zhaomin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769694/ https://www.ncbi.nlm.nih.gov/pubmed/36377931 http://dx.doi.org/10.1128/spectrum.03877-22

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