Cargando…

Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory tract or the intestine—to secondary replication sites—skin o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Helgers, Leanne C., Bhoekhan, Michel S., Pajkrt, Dasja, Wolthers, Katja C., Geijtenbeek, Teunis B. H., Sridhar, Adithya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769767/ https://www.ncbi.nlm.nih.gov/pubmed/36222686 http://dx.doi.org/10.1128/spectrum.02822-22

Ejemplares similares

Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism
por: Sridhar, Adithya, et al.
Publicado: (2022)

World-Wide Prevalence and Genotype Distribution of Enteroviruses
por: Brouwer, Lieke, et al.
Publicado: (2021)

Non-Polio Enterovirus C Replicate in Both Airway and Intestine Organotypic Cultures
por: Moreni, Giulia, et al.
Publicado: (2023)

Put Some Guts into It: Intestinal Organoid Models to Study Viral Infection
por: García-Rodríguez, Inés, et al.
Publicado: (2020)

Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant
por: van der Sanden, Sabine M. G., et al.
Publicado: (2018)

Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model
por: Aknouch, Ikrame, et al.
Publicado: (2023)

Parechovirus A Pathogenesis and the Enigma of Genotype A-3
por: Sridhar, Adithya, et al.
Publicado: (2019)

Enterovirus D68 serosurvey: evidence for endemic circulation in the Netherlands, 2006 to 2016
por: Karelehto, Eveliina, et al.
Publicado: (2019)

Infection and transmission of SARS‐CoV‐2 depend on heparan sulfate proteoglycans
por: Bermejo‐Jambrina, Marta, et al.
Publicado: (2021)

Parechovirus A Infection of the Intestinal Epithelium: Differences Between Genotypes A1 and A3
por: García-Rodríguez, Inés, et al.
Publicado: (2021)

Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation
por: Kobayashi, Kyousuke, et al.
Publicado: (2020)

Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells
por: Ceballos, Ana, et al.
Publicado: (2009)

A Perspective on Organoids for Virology Research
por: Sridhar, Adithya, et al.
Publicado: (2020)

A beginner’s guide on the use of brain organoids for neuroscientists: a systematic review
por: Mulder, Lance A., et al.
Publicado: (2023)

Variant enterovirus A71 found in immune-suppressed patient binds to heparan sulfate and exhibits neurotropism in B-cell-depleted mice
por: Weng, Kuo-Feng, et al.
Publicado: (2023)

Transmission of Zika virus by dendritic cell subsets in skin and vaginal mucosa
por: Eder, Julia, et al.
Publicado: (2023)

Recombination Analysis of Non-Poliovirus Members of the Enterovirus C Species: Restriction of Recombination Events to Members of the Same 3DPol Cluster
por: Brouwer, Lieke, et al.
Publicado: (2020)

A Single Mutation in the VP1 Gene of Enterovirus 71 Enhances Viral Binding to Heparan Sulfate and Impairs Viral Pathogenicity in Mice
por: Ke, Xianliang, et al.
Publicado: (2020)

Parechovirus A prevalence in adults in The Netherlands
por: Brouwer, Lieke, et al.
Publicado: (2020)

P07-08. Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells
por: Lenicov, F Remes, et al.
Publicado: (2009)

Neutralising Antibodies against Enterovirus and Parechovirus in IVIG Reflect General Circulation: A Tool for Sero-Surveillance
por: Couderé, Karen, et al.
Publicado: (2021)

Exosomes cloak the virion to transmit Enterovirus 71 non-lytically
por: Gu, Jiaqi, et al.
Publicado: (2019)

Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery
por: Masmoudi, Fatma, et al.
Publicado: (2023)

Human Brain Organoids as Models for Central Nervous System Viral Infection
por: Depla, Josse A., et al.
Publicado: (2022)

The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate
por: Nishimura, Yorihiro, et al.
Publicado: (2015)

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism
por: Tseligka, Eirini D., et al.
Publicado: (2018)

Dynamic Interaction of Enterovirus 71 and Dendritic Cells in Infected Neonatal Rhesus Macaques
por: Zhao, Ting, et al.
Publicado: (2017)

Heparan sulfates and heparan sulfate binding proteins in sepsis
por: Liao, Yi-En, et al.
Publicado: (2023)

Comorbidities, clinical characteristics and outcomes of COVID-19 in pediatric patients in a tertiary medical center in the Netherlands
por: Biharie, Amrita, et al.
Publicado: (2022)

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
por: Nagarajan, Arvindhan, et al.
Publicado: (2018)

Cell and tissue tropism of enterovirus 71 and other enteroviruses infections
por: Lin, Jing-Yi, et al.
Publicado: (2014)

MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
por: Shi, Weifeng, et al.
Publicado: (2014)

Tyrosine Sulfation of the Amino Terminus of PSGL-1 Is Critical for Enterovirus 71 Infection
por: Nishimura, Yorihiro, et al.
Publicado: (2010)

Receptors for enterovirus 71
por: Yamayoshi, Seiya, et al.
Publicado: (2014)

Polarized Entry of Human Parechoviruses in the Airway Epithelium
por: Karelehto, Eveliina, et al.
Publicado: (2018)

Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs
por: Stroulios, Georgios, et al.
Publicado: (2022)

Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain
por: Depla, Josse A., et al.
Publicado: (2020)

The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection
por: Ren, Xiao-Xin, et al.
Publicado: (2014)

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development
por: Kinnunen, Tarja K.
Publicado: (2014)

Enterovirus 71 Outbreak, Brunei
por: AbuBakar, Sazaly, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_d4up95kpbqhqvh3r9hsq6dftug