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25-Hydroxycholesterol Mediates Cholesterol Metabolism to Restrict Porcine Deltacoronavirus Infection via Suppression of Transforming Growth Factor β1
Porcine deltacoronavirus (PDCoV), an emerging enteropathogenic coronavirus in pigs, is one of the major pathogens for lethal watery diarrhea in piglets and poses a threat to public health because of its potential for interspecies transmission to humans. 25-Hydroxycholesterol (25HC), a derivative of...
Autores principales: | Zhang, Jialu, Yang, Guanghui, Wang, Xuefei, Zhu, Yaohong, Wang, Jiufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769798/ https://www.ncbi.nlm.nih.gov/pubmed/36314946 http://dx.doi.org/10.1128/spectrum.02198-22 |
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