Cargando…
Anidulafungin Treatment Blocks the Sexual Cycle of Pneumocystis murina and Prevents Growth and Survival without Rescue by an Alternative Mode of Replication
The proposed life cycle of fungi in the genus Pneumocystis has typically included both an asexual cycle via binary fission and a sexual cycle. Until recently, the strategy used for sexual replication was largely unknown, but genomic and functional assays now support a mode known as primary homothall...
Autores principales: | Cushion, Melanie T., Ashbaugh, Alan, Sayson, Steven G., Mosley, Christopher, Hauser, Philippe M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769855/ https://www.ncbi.nlm.nih.gov/pubmed/36287071 http://dx.doi.org/10.1128/spectrum.02906-22 |
Ejemplares similares
-
Gene Expression of Pneumocystis murina after Treatment with Anidulafungin Results in Strong Signals for Sexual Reproduction, Cell Wall Integrity, and Cell Cycle Arrest, Indicating a Requirement for Ascus Formation for Proliferation
por: Cushion, Melanie T., et al.
Publicado: (2018) -
The Effects of Sex and Strain on Pneumocystis murina Fungal Burdens in Mice
por: Macioce-Tisdale, Nikeya L., et al.
Publicado: (2022) -
The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models
por: Cushion, Melanie T., et al.
Publicado: (2021) -
Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure
por: Linke, Michael J, et al.
Publicado: (2009) -
The Persistent Challenge of Pneumocystis Growth Outside the Mammalian Lung: Past and Future Approaches
por: Cushion, Melanie T., et al.
Publicado: (2021)