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Dioxane-Linked Novel Bacterial Topoisomerase Inhibitors Exhibit Bactericidal Activity against Planktonic and Biofilm Staphylococcus aureus In Vitro

The development of novel treatments for Staphylococcus aureus infections remains a high priority worldwide. We previously reported compounds 0147 and 0186, novel bacterial topoisomerase inhibitors (NBTIs) with potent antibacterial activity against S. aureus, including methicillin-resistant S. aureus...

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Detalles Bibliográficos
Autores principales:	Chen, Anna, Dellos-Nolan, Sheri, Lu, Yanran, West, Jason S., Wozniak, Daniel J., Mitton-Fry, Mark J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769912/ https://www.ncbi.nlm.nih.gov/pubmed/36250857 http://dx.doi.org/10.1128/spectrum.02056-22

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