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Long-Term and Low-Level Envelope C2V3 Stimulation by Highly Diverse Virus Isolates Leads to Frequent Development of Broad and Elite Antibody Neutralization in HIV-1-Infected Individuals

A minority of HIV-1-infected patients produce broadly neutralizing antibodies (bNAbs). Identification of viral and host correlates of bNAb production may help develop vaccines. We aimed to characterize the neutralizing response and viral and host-associated factors in Angola, which has one of the ol...

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Detalles Bibliográficos
Autores principales: Martin, Francisco, Marcelino, José Maria, Palladino, Claudia, Bártolo, Inês, Tracana, Susana, Moranguinho, Inês, Gonçalves, Paloma, Mateus, Rita, Calado, Rita, Borrego, Pedro, Leitner, Thomas, Clemente, Sofia, Taveira, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769935/
https://www.ncbi.nlm.nih.gov/pubmed/36445130
http://dx.doi.org/10.1128/spectrum.01634-22