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Development and Assessment of a Novel Whole-Gene-Based Targeted Next-Generation Sequencing Assay for Detecting the Susceptibility of Mycobacterium tuberculosis to 14 Drugs

Targeted next-generation sequencing (tNGS) has emerged as an alternative method for detecting drug-resistant tuberculosis (DR-TB). To provide comprehensive drug susceptibility information and to address mutations missed by available commercial molecular diagnostics, we developed and evaluated a tNGS...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Han, Xiao, Yu-Xin, Hsiao, Hseuh-Chien, Jou, Ruwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769975/
https://www.ncbi.nlm.nih.gov/pubmed/36255328
http://dx.doi.org/10.1128/spectrum.02605-22