Cargando…

Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review

Relapsing polychondritis (RP) most commonly presents as inflammation and degeneration of cartilaginous tissue in the auricles, nasal septum, and lungs (in severe instances). RP is a rare autoimmune condition associated with other autoimmune diseases in 30% of cases. The prevalence of gastrointestina...

Descripción completa

Detalles Bibliográficos
Autores principales: Bickford, David D, Ritter, Thomas, Jha, Pinky, Paudel, Hari R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770012/
https://www.ncbi.nlm.nih.gov/pubmed/36569669
http://dx.doi.org/10.7759/cureus.31738
_version_ 1784854499355000832
author Bickford, David D
Ritter, Thomas
Jha, Pinky
Paudel, Hari R
author_facet Bickford, David D
Ritter, Thomas
Jha, Pinky
Paudel, Hari R
author_sort Bickford, David D
collection PubMed
description Relapsing polychondritis (RP) most commonly presents as inflammation and degeneration of cartilaginous tissue in the auricles, nasal septum, and lungs (in severe instances). RP is a rare autoimmune condition associated with other autoimmune diseases in 30% of cases. The prevalence of gastrointestinal involvement with RP is tenuous; however, there is a growing collection of case studies associating auricular chondritis with concomitant inflammatory bowel disease (IBD), including both ulcerative colitis and Crohn’s disease. We report the case of a 35-year-old patient presenting with autoimmune pancreatitis, with a past medical history of Crohn’s disease, primary sclerosing cholangitis (PSC), and suspected RP. Although RP is rare, the disease’s multiple clinical presentations and recurrent episodic nature can cause significant diagnostic delays and are often overlooked by physicians. Thus, low disease prevalence may be due to under-recognition and under-reporting of disease symptoms. As RP is a clinical diagnosis, increased awareness of the disease presentation and clinical characteristics may increase disease recognition and improve treatment outcomes.
format Online
Article
Text
id pubmed-9770012
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-97700122022-12-22 Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review Bickford, David D Ritter, Thomas Jha, Pinky Paudel, Hari R Cureus Internal Medicine Relapsing polychondritis (RP) most commonly presents as inflammation and degeneration of cartilaginous tissue in the auricles, nasal septum, and lungs (in severe instances). RP is a rare autoimmune condition associated with other autoimmune diseases in 30% of cases. The prevalence of gastrointestinal involvement with RP is tenuous; however, there is a growing collection of case studies associating auricular chondritis with concomitant inflammatory bowel disease (IBD), including both ulcerative colitis and Crohn’s disease. We report the case of a 35-year-old patient presenting with autoimmune pancreatitis, with a past medical history of Crohn’s disease, primary sclerosing cholangitis (PSC), and suspected RP. Although RP is rare, the disease’s multiple clinical presentations and recurrent episodic nature can cause significant diagnostic delays and are often overlooked by physicians. Thus, low disease prevalence may be due to under-recognition and under-reporting of disease symptoms. As RP is a clinical diagnosis, increased awareness of the disease presentation and clinical characteristics may increase disease recognition and improve treatment outcomes. Cureus 2022-11-21 /pmc/articles/PMC9770012/ /pubmed/36569669 http://dx.doi.org/10.7759/cureus.31738 Text en Copyright © 2022, Bickford et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Bickford, David D
Ritter, Thomas
Jha, Pinky
Paudel, Hari R
Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title_full Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title_fullStr Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title_full_unstemmed Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title_short Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
title_sort relapsing polychondritis in a patient with auricular chondritis and inflammatory bowel disease: a case report with literature review
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770012/
https://www.ncbi.nlm.nih.gov/pubmed/36569669
http://dx.doi.org/10.7759/cureus.31738
work_keys_str_mv AT bickforddavidd relapsingpolychondritisinapatientwithauricularchondritisandinflammatoryboweldiseaseacasereportwithliteraturereview
AT ritterthomas relapsingpolychondritisinapatientwithauricularchondritisandinflammatoryboweldiseaseacasereportwithliteraturereview
AT jhapinky relapsingpolychondritisinapatientwithauricularchondritisandinflammatoryboweldiseaseacasereportwithliteraturereview
AT paudelharir relapsingpolychondritisinapatientwithauricularchondritisandinflammatoryboweldiseaseacasereportwithliteraturereview