EARLY-LIFE PROTEIN TRANSLATION SPIKE DRIVES AGING VIA JUVENILE HORMONE/GERMLINE STEM CELL SIGNALING

Protein translation (PT) is high in early-adulthood across invertebrates, rodents, and humans but sharply declines thereafter. It has been implicitly assumed that elevated PT at young ages is beneficial to health and PT ends up dropping as a passive byproduct of aging. However, whether this holds tr...

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Detalles Bibliográficos
Autores principales: Kim, Harper, Parker, Danitra, Hardiman, Madison, Munkácsy, Erin, Austad, Steven, Bai, Yi-dong, Mobley, James, Pickering, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770201/
http://dx.doi.org/10.1093/geroni/igac059.520

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