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IL1β Expression Driven by Androgen Receptor Absence or Inactivation Promotes Prostate Cancer Bone Metastasis

We report the inverse association between the expression of androgen receptor (AR) and IL1β in a cohort of patients with metastatic castration-resistant prostate cancer. We also discovered that AR represses the IL1β gene by binding an androgen response element half-site located within the promoter,...

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Detalles Bibliográficos
Autores principales:	DiNatale, Anthony, Worrede, Asurayya, Iqbal, Waleed, Marchioli, Michael, Toth, Allison, Sjöström, Martin, Zhu, Xiaolin, Corey, Eva, Feng, Felix Y., Zhou, Wanding, Fatatis, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770512/ https://www.ncbi.nlm.nih.gov/pubmed/36561929 http://dx.doi.org/10.1158/2767-9764.CRC-22-0262

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