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THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA

Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without...

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Autores principales: Hunt, Lauren, Morrison, Sean, Gan, Siqi, Espejo, Edie, Boscardin, W John, Rodin, Rebecca, Ornstein, Katherine, Smith, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770554/
http://dx.doi.org/10.1093/geroni/igac059.1625
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author Hunt, Lauren
Morrison, Sean
Gan, Siqi
Espejo, Edie
Boscardin, W John
Rodin, Rebecca
Ornstein, Katherine
Smith, Alexander
author_facet Hunt, Lauren
Morrison, Sean
Gan, Siqi
Espejo, Edie
Boscardin, W John
Rodin, Rebecca
Ornstein, Katherine
Smith, Alexander
author_sort Hunt, Lauren
collection PubMed
description Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without dementia (PWoD). Using data from the Health and Retirement Study linked to Medicare claims, we estimated the impact of hip fracture and pneumonia on risk of mortality among 700 PWD and 12,438 PWoD using a Cox proportional hazards model. PWD had a higher risk of mortality both in the case of hip fracture (HR 1.64, 95% CI 1.31, 1.96) and pneumonia (HR 1.21 95% CI 1.09, 1.34) compared to PWoD who experienced those events. This study provides evidence that dementia may increase mortality after a disruptive medical event and suggests that the clinical course of dementia may not always be slow and gradual.
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spelling pubmed-97705542022-12-22 THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA Hunt, Lauren Morrison, Sean Gan, Siqi Espejo, Edie Boscardin, W John Rodin, Rebecca Ornstein, Katherine Smith, Alexander Innov Aging Abstracts Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without dementia (PWoD). Using data from the Health and Retirement Study linked to Medicare claims, we estimated the impact of hip fracture and pneumonia on risk of mortality among 700 PWD and 12,438 PWoD using a Cox proportional hazards model. PWD had a higher risk of mortality both in the case of hip fracture (HR 1.64, 95% CI 1.31, 1.96) and pneumonia (HR 1.21 95% CI 1.09, 1.34) compared to PWoD who experienced those events. This study provides evidence that dementia may increase mortality after a disruptive medical event and suggests that the clinical course of dementia may not always be slow and gradual. Oxford University Press 2022-12-20 /pmc/articles/PMC9770554/ http://dx.doi.org/10.1093/geroni/igac059.1625 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Hunt, Lauren
Morrison, Sean
Gan, Siqi
Espejo, Edie
Boscardin, W John
Rodin, Rebecca
Ornstein, Katherine
Smith, Alexander
THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title_full THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title_fullStr THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title_full_unstemmed THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title_short THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
title_sort effect of disruptive medical events on mortality in people with and without dementia
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770554/
http://dx.doi.org/10.1093/geroni/igac059.1625
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