Cargando…
THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA
Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770554/ http://dx.doi.org/10.1093/geroni/igac059.1625 |
_version_ | 1784854627079946240 |
---|---|
author | Hunt, Lauren Morrison, Sean Gan, Siqi Espejo, Edie Boscardin, W John Rodin, Rebecca Ornstein, Katherine Smith, Alexander |
author_facet | Hunt, Lauren Morrison, Sean Gan, Siqi Espejo, Edie Boscardin, W John Rodin, Rebecca Ornstein, Katherine Smith, Alexander |
author_sort | Hunt, Lauren |
collection | PubMed |
description | Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without dementia (PWoD). Using data from the Health and Retirement Study linked to Medicare claims, we estimated the impact of hip fracture and pneumonia on risk of mortality among 700 PWD and 12,438 PWoD using a Cox proportional hazards model. PWD had a higher risk of mortality both in the case of hip fracture (HR 1.64, 95% CI 1.31, 1.96) and pneumonia (HR 1.21 95% CI 1.09, 1.34) compared to PWoD who experienced those events. This study provides evidence that dementia may increase mortality after a disruptive medical event and suggests that the clinical course of dementia may not always be slow and gradual. |
format | Online Article Text |
id | pubmed-9770554 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-97705542022-12-22 THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA Hunt, Lauren Morrison, Sean Gan, Siqi Espejo, Edie Boscardin, W John Rodin, Rebecca Ornstein, Katherine Smith, Alexander Innov Aging Abstracts Disruptive medical events such as pneumonia and hip fracture occur more frequently among older adults with dementia than those without dementia. It is not well-understood whether these events increase the risk of mortality to a greater extent for people with dementia (PWD) compared to people without dementia (PWoD). Using data from the Health and Retirement Study linked to Medicare claims, we estimated the impact of hip fracture and pneumonia on risk of mortality among 700 PWD and 12,438 PWoD using a Cox proportional hazards model. PWD had a higher risk of mortality both in the case of hip fracture (HR 1.64, 95% CI 1.31, 1.96) and pneumonia (HR 1.21 95% CI 1.09, 1.34) compared to PWoD who experienced those events. This study provides evidence that dementia may increase mortality after a disruptive medical event and suggests that the clinical course of dementia may not always be slow and gradual. Oxford University Press 2022-12-20 /pmc/articles/PMC9770554/ http://dx.doi.org/10.1093/geroni/igac059.1625 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstracts Hunt, Lauren Morrison, Sean Gan, Siqi Espejo, Edie Boscardin, W John Rodin, Rebecca Ornstein, Katherine Smith, Alexander THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title | THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title_full | THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title_fullStr | THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title_full_unstemmed | THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title_short | THE EFFECT OF DISRUPTIVE MEDICAL EVENTS ON MORTALITY IN PEOPLE WITH AND WITHOUT DEMENTIA |
title_sort | effect of disruptive medical events on mortality in people with and without dementia |
topic | Abstracts |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770554/ http://dx.doi.org/10.1093/geroni/igac059.1625 |
work_keys_str_mv | AT huntlauren theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT morrisonsean theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT gansiqi theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT espejoedie theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT boscardinwjohn theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT rodinrebecca theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT ornsteinkatherine theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT smithalexander theeffectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT huntlauren effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT morrisonsean effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT gansiqi effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT espejoedie effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT boscardinwjohn effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT rodinrebecca effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT ornsteinkatherine effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia AT smithalexander effectofdisruptivemedicaleventsonmortalityinpeoplewithandwithoutdementia |