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MODELING REACTIVATED HETEROCHROMATIN USING AN AGING 3D CELL MODEL
Chromatin state and dynamics is modulated by chromatin interacting proteins, in particular histones and their post-translational modifications. We investigate the chromatin-bound proteome in aging to understand how DNA readout is misregulated in senescent cells. We focus on domains of reactivated he...
Autores principales: | Sidoli, Simone, Stransky, Stephanie, Cutler, Ronald, Graff, Sarah, Aguilan, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770697/ http://dx.doi.org/10.1093/geroni/igac059.103 |
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