Cargando…

MODELING REACTIVATED HETEROCHROMATIN USING AN AGING 3D CELL MODEL

Chromatin state and dynamics is modulated by chromatin interacting proteins, in particular histones and their post-translational modifications. We investigate the chromatin-bound proteome in aging to understand how DNA readout is misregulated in senescent cells. We focus on domains of reactivated he...

Descripción completa

Detalles Bibliográficos
Autores principales: Sidoli, Simone, Stransky, Stephanie, Cutler, Ronald, Graff, Sarah, Aguilan, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770697/
http://dx.doi.org/10.1093/geroni/igac059.103

Ejemplares similares