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Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells

Understanding cancer metastasis at the proteoform level is crucial for discovering previously unknown protein biomarkers for cancer diagnosis and drug development. We present the first top-down proteomics (TDP) study of a pair of isogenic human nonmetastatic and metastatic colorectal cancer (CRC) ce...

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Detalles Bibliográficos
Autores principales:	McCool, Elijah N., Xu, Tian, Chen, Wenrong, Beller, Nicole C., Nolan, Scott M., Hummon, Amanda B., Liu, Xiaowen, Sun, Liangliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770947/ https://www.ncbi.nlm.nih.gov/pubmed/36542699 http://dx.doi.org/10.1126/sciadv.abq6348

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