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OXR1 STABILIZES THE RETROMER TO EXTEND LIFESPAN AND NEURONAL HEALTH BY DIETARY RESTRICTION
Dietary restriction (DR) delays aging and neurodegeneration, but the mechanisms behind this remain unclear. We reared over 150 fully sequenced fly strains from the Drosophila Genetic Reference Panel under ad libitum feeding or diet-restricted conditions and measured lifespan as well as healthspan to...
Autores principales: | Wilson, Kenneth, Bar, Sudipta, Dammer, Eric, Schilling, Birgit, Seyfried, Nicholas, Bellen, Hugo, Ellerby, Lisa, Kapahi, Pankaj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9770986/ http://dx.doi.org/10.1093/geroni/igac059.2661 |
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