Cargando…

The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study

BACKGROUND: Human wellbeing has been linked with lifestyle factors such as physical activity, diet balance, sleep quality, depression, and anxiety. However, few studies illustrate the relationship between such lifestyle factors and HPV infection. In this study, we investigated the association betwee...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yantao, Liu, Mengping, Huang, Peng, Wang, Wenxiang, Jiang, Yuxin, Yang, Zhongzhou, Wang, Anli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771376/
https://www.ncbi.nlm.nih.gov/pubmed/36568201
http://dx.doi.org/10.3389/fonc.2022.1043937
_version_ 1784854813893197824
author Li, Yantao
Liu, Mengping
Huang, Peng
Wang, Wenxiang
Jiang, Yuxin
Yang, Zhongzhou
Wang, Anli
author_facet Li, Yantao
Liu, Mengping
Huang, Peng
Wang, Wenxiang
Jiang, Yuxin
Yang, Zhongzhou
Wang, Anli
author_sort Li, Yantao
collection PubMed
description BACKGROUND: Human wellbeing has been linked with lifestyle factors such as physical activity, diet balance, sleep quality, depression, and anxiety. However, few studies illustrate the relationship between such lifestyle factors and HPV infection. In this study, we investigated the association between lifestyle factors, age, disease status and HPV infection. PARTICIPANTS AND METHODS: Participants were recruited through a digital eHealth platform in Shenzhen, Mainland China. Both lifestyle factors and cervicovaginal mucus (CVM) samples to test for HPV outcomes were collected from each participant as a cross-sectional study. In addition, the eHealth platform recorded age and current or history diseases, which were adjusted to apply for both univariable and multivariable logistic regression. Furthermore, lifestyle factors were categorized as different levels to conduct stratification analysis. RESULTS: We recruited 149 HPV positive and 346 HPV negative participants through HPV detection. Physical activity and diet balance were significantly associated with HPV infection in lifestyle factors (P values < 0.001) after adjusting for age and current or history diseases. However, stratified analysis showed three factors were insignificant for HPV infection – namely, sleep quality, depression, and anxiety. Most HPV infections involved a sole HPV serotype (83%), and diet balance was the most significant difference between sole and multiple HPV infections. CONCLUSIONS: Among lifestyle factors, physical inactivity or diet imbalance can significantly increase HPV infection risk. In particular, diet balance might be related to the number of HPV serotypes. Our results suggest that exercising and regulating diet may reduce the risk of HPV infection.
format Online
Article
Text
id pubmed-9771376
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-97713762022-12-22 The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study Li, Yantao Liu, Mengping Huang, Peng Wang, Wenxiang Jiang, Yuxin Yang, Zhongzhou Wang, Anli Front Oncol Oncology BACKGROUND: Human wellbeing has been linked with lifestyle factors such as physical activity, diet balance, sleep quality, depression, and anxiety. However, few studies illustrate the relationship between such lifestyle factors and HPV infection. In this study, we investigated the association between lifestyle factors, age, disease status and HPV infection. PARTICIPANTS AND METHODS: Participants were recruited through a digital eHealth platform in Shenzhen, Mainland China. Both lifestyle factors and cervicovaginal mucus (CVM) samples to test for HPV outcomes were collected from each participant as a cross-sectional study. In addition, the eHealth platform recorded age and current or history diseases, which were adjusted to apply for both univariable and multivariable logistic regression. Furthermore, lifestyle factors were categorized as different levels to conduct stratification analysis. RESULTS: We recruited 149 HPV positive and 346 HPV negative participants through HPV detection. Physical activity and diet balance were significantly associated with HPV infection in lifestyle factors (P values < 0.001) after adjusting for age and current or history diseases. However, stratified analysis showed three factors were insignificant for HPV infection – namely, sleep quality, depression, and anxiety. Most HPV infections involved a sole HPV serotype (83%), and diet balance was the most significant difference between sole and multiple HPV infections. CONCLUSIONS: Among lifestyle factors, physical inactivity or diet imbalance can significantly increase HPV infection risk. In particular, diet balance might be related to the number of HPV serotypes. Our results suggest that exercising and regulating diet may reduce the risk of HPV infection. Frontiers Media S.A. 2022-12-07 /pmc/articles/PMC9771376/ /pubmed/36568201 http://dx.doi.org/10.3389/fonc.2022.1043937 Text en Copyright © 2022 Li, Liu, Huang, Wang, Jiang, Yang and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Li, Yantao
Liu, Mengping
Huang, Peng
Wang, Wenxiang
Jiang, Yuxin
Yang, Zhongzhou
Wang, Anli
The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title_full The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title_fullStr The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title_full_unstemmed The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title_short The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study
title_sort lifestyle factors of physical activity and diet balance associated with hpv infection in china: the cross-sectional study
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771376/
https://www.ncbi.nlm.nih.gov/pubmed/36568201
http://dx.doi.org/10.3389/fonc.2022.1043937
work_keys_str_mv AT liyantao thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT liumengping thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT huangpeng thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT wangwenxiang thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT jiangyuxin thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT yangzhongzhou thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT wanganli thelifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT liyantao lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT liumengping lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT huangpeng lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT wangwenxiang lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT jiangyuxin lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT yangzhongzhou lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy
AT wanganli lifestylefactorsofphysicalactivityanddietbalanceassociatedwithhpvinfectioninchinathecrosssectionalstudy