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Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study

Objective  The spinal column is one of the most prevalent regions for metastasis, with an increasing frequency of spinal metastases. Spinal cord metastatic tumor damages the vertebral body, weakens the spinal support, and exerts mass effect on the spinal cord. Overzealous surgical intervention does...

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Autores principales: Hashmi, Syed Muhammad Maroof, Hammoud, Ibrahim, Kumar, Pranaw, Sartaj, Afaq Ali, Ghosh, Kaushik, Ray, Arupratan, Golash, Aprajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771617/
https://www.ncbi.nlm.nih.gov/pubmed/36570752
http://dx.doi.org/10.1055/s-0042-1758846
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author Hashmi, Syed Muhammad Maroof
Hammoud, Ibrahim
Kumar, Pranaw
Sartaj, Afaq Ali
Ghosh, Kaushik
Ray, Arupratan
Golash, Aprajay
author_facet Hashmi, Syed Muhammad Maroof
Hammoud, Ibrahim
Kumar, Pranaw
Sartaj, Afaq Ali
Ghosh, Kaushik
Ray, Arupratan
Golash, Aprajay
author_sort Hashmi, Syed Muhammad Maroof
collection PubMed
description Objective  The spinal column is one of the most prevalent regions for metastasis, with an increasing frequency of spinal metastases. Spinal cord metastatic tumor damages the vertebral body, weakens the spinal support, and exerts mass effect on the spinal cord. Overzealous surgical intervention does not provide any additional benefit in most of the spinal metastasis due to shorter life expectancy. The principal goal of this study is to analyze the outcome of various surgical treatments offered to patients with metastatic spinal cord compression (MSCC). Methods  Retrospective cohort study including all patients that underwent surgical intervention for MSCC from March 2013 to March 2020. Results  A total of 198 patients were included, 113 males and 85 females; the mean age was 62 years. The most common primary cancer was prostate (21.71%) followed by hematological (20.07%) and lung (16.66%). At 6-month postsurgery, 68.68% of patients were Frankel grade D or E (vs. 23.23% preoperatively), 16.6% were grade C (vs 57% preoperatively), and 14.64% were grade A or B (vs. 19.69% preoperatively). Pain on numeric rating scale was decreased from 6.38 ± 3.08 to 3.39 ± 0.73 at 24 hours postsurgery and 1.94 ± 0.67 at 6 months. Conclusion  This study found that the majority of patients, undergoing minimally invasive spinal stabilization and decompression for metastatic spinal tumors, have better quality of life, analgesia, and mobility. In conclusion, treatment for spinal metastases should be individualized and a multidisciplinary approach is needed.
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spelling pubmed-97716172022-12-22 Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study Hashmi, Syed Muhammad Maroof Hammoud, Ibrahim Kumar, Pranaw Sartaj, Afaq Ali Ghosh, Kaushik Ray, Arupratan Golash, Aprajay Asian J Neurosurg Objective  The spinal column is one of the most prevalent regions for metastasis, with an increasing frequency of spinal metastases. Spinal cord metastatic tumor damages the vertebral body, weakens the spinal support, and exerts mass effect on the spinal cord. Overzealous surgical intervention does not provide any additional benefit in most of the spinal metastasis due to shorter life expectancy. The principal goal of this study is to analyze the outcome of various surgical treatments offered to patients with metastatic spinal cord compression (MSCC). Methods  Retrospective cohort study including all patients that underwent surgical intervention for MSCC from March 2013 to March 2020. Results  A total of 198 patients were included, 113 males and 85 females; the mean age was 62 years. The most common primary cancer was prostate (21.71%) followed by hematological (20.07%) and lung (16.66%). At 6-month postsurgery, 68.68% of patients were Frankel grade D or E (vs. 23.23% preoperatively), 16.6% were grade C (vs 57% preoperatively), and 14.64% were grade A or B (vs. 19.69% preoperatively). Pain on numeric rating scale was decreased from 6.38 ± 3.08 to 3.39 ± 0.73 at 24 hours postsurgery and 1.94 ± 0.67 at 6 months. Conclusion  This study found that the majority of patients, undergoing minimally invasive spinal stabilization and decompression for metastatic spinal tumors, have better quality of life, analgesia, and mobility. In conclusion, treatment for spinal metastases should be individualized and a multidisciplinary approach is needed. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-12-10 /pmc/articles/PMC9771617/ /pubmed/36570752 http://dx.doi.org/10.1055/s-0042-1758846 Text en Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Hashmi, Syed Muhammad Maroof
Hammoud, Ibrahim
Kumar, Pranaw
Sartaj, Afaq Ali
Ghosh, Kaushik
Ray, Arupratan
Golash, Aprajay
Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title_full Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title_fullStr Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title_full_unstemmed Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title_short Outcome of Surgical Treatment for Metastatic Spinal Cord Compression: A Single-Center Retrospective Study
title_sort outcome of surgical treatment for metastatic spinal cord compression: a single-center retrospective study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771617/
https://www.ncbi.nlm.nih.gov/pubmed/36570752
http://dx.doi.org/10.1055/s-0042-1758846
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