Cargando…

Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism

OBJECTIVE: The gastrointestinal tract affects physiological activities and behavior by secreting hormones and generating signals through the activation of nutrient sensors. GPR119, a lipid sensor, is indirectly involved in the secretion of incretins, such as glucagon-like peptide-1 and glucose-depen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Igarashi, Miki, Hayakawa, Tetsuhiko, Tanabe, Haruka, Watanabe, Keita, Nishida, Akari, Kimura, Ikuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771719/ https://www.ncbi.nlm.nih.gov/pubmed/36462626 http://dx.doi.org/10.1016/j.molmet.2022.101649

Ejemplares similares

Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions
por: Miyamoto, Junki, et al.
Publicado: (2019)

Potential Metabolic and Behavioural Roles of the Putative Endo- cannabinoid Receptors GPR18, GPR55 and GPR119 in Feeding
por: Ramírez-Orozco, Ricardo E., et al.
Publicado: (2019)

β-Cell Inactivation of Gpr119 Unmasks Incretin Dependence of GPR119-Mediated Glucoregulation
por: Panaro, Brandon L., et al.
Publicado: (2017)

Dietary oleic acid contributes to the regulation of food intake through the synthesis of intestinal oleoylethanolamide
por: Igarashi, Miki, et al.
Publicado: (2023)

Synthetic dietary inulin, Fuji FF, delays development of diet-induced obesity by improving gut microbiota profiles and increasing short-chain fatty acid production
por: Igarashi, Miki, et al.
Publicado: (2020)

Oleoylethanolamide Exhibits GPR119-Dependent Inhibition of Osteoclast Function and GPR119-Independent Promotion of Osteoclast Apoptosis
por: Kim, Hyun-Ju, et al.
Publicado: (2020)

Involvement of Gut Microbial Metabolites Derived from Diet on Host Energy Homeostasis
por: Nishida, Akari, et al.
Publicado: (2022)

GPR55 and GPR119 Receptors Contribute to the Processing of Neuropathic Pain in Rats
por: Zúñiga-Romero, Ángel, et al.
Publicado: (2022)

GPR119 and GPR55 as Receptors for Fatty Acid Ethanolamides, Oleoylethanolamide and Palmitoylethanolamide
por: Im, Dong-Soon
Publicado: (2021)

Chemistry and Hypoglycemic Activity of GPR119 Agonist ZB-16
por: Tyurenkov, Ivan N., et al.
Publicado: (2018)

Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice
por: Higuchi, Sei, et al.
Publicado: (2020)

OR24-01 Mutational Study of the GPR119 Receptor Binding Site
por: Rosales, Matthew D, et al.
Publicado: (2020)

Activation and signaling mechanism revealed by GPR119-G(s) complex structures
por: Qian, Yuxia, et al.
Publicado: (2022)

Microbial biotransformation to obtain stilbene methylglucoside with GPR119 agonistic activity
por: Peng, Yu, et al.
Publicado: (2023)

Regulation of Energy Homeostasis by GPR41
por: Inoue, Daisuke, et al.
Publicado: (2014)

Dietary Medium-Chain Triglyceride Decanoate Affects Glucose Homeostasis Through GPR84-Mediated GLP-1 Secretion in Mice
por: Nonaka, Hazuki, et al.
Publicado: (2022)

Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84
por: Ohue-Kitano, Ryuji, et al.
Publicado: (2023)

GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell
por: Lauffer, Lina M., et al.
Publicado: (2009)

Angelica dahurica Extracts Improve Glucose Tolerance through the Activation of GPR119
por: Park, Eun-Young, et al.
Publicado: (2016)

The SCFA Receptor GPR43 and Energy Metabolism
por: Kimura, Ikuo, et al.
Publicado: (2014)

GPR119 agonist enhances gefitinib responsiveness through lactate-mediated inhibition of autophagy
por: Im, Ji Hye, et al.
Publicado: (2018)

Correction: GPR119 agonist enhances gefitinib responsiveness through lactate-mediatedinhibition of autophagy
por: Im, Ji Hye, et al.
Publicado: (2022)

Microbiota metabolite short chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43
por: Wu, Wei, et al.
Publicado: (2016)

Peptide YY Is Critical for Acylethanolamine Receptor Gpr119-Induced Activation of Gastrointestinal Mucosal Responses
por: Cox, Helen M., et al.
Publicado: (2010)

Stimulating β-Cell Regeneration by Combining a GPR119 Agonist with a DPP-IV Inhibitor
por: Ansarullah,, et al.
Publicado: (2013)

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells
por: Hodge, Daryl, et al.
Publicado: (2016)

Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa
por: Tough, Iain R, et al.
Publicado: (2018)

Formation of βTC3 and MIN6 Pseudoislets Changes the Expression Pattern of Gpr40, Gpr55, and Gpr119 Receptors and Improves Lysophosphatidylcholines-Potentiated Glucose-Stimulated Insulin Secretion
por: Drzazga, Anna, et al.
Publicado: (2020)

$^{119}$Sn Mössbauer study of the implantation behaviour of $^{119}$In, $^{119}$Sn, $^{119m}$Sn, $^{119}$Sb and $^{119m}$Te ions in SiC
por: Petersen, J W, et al.
Publicado: (1985)

Gut Microbiota Dysbiosis Drives and Implies Novel Therapeutic Strategies for Diabetes Mellitus and Related Metabolic Diseases
por: Li, Xuan, et al.
Publicado: (2017)

Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids
por: Watanabe, Keita, et al.
Publicado: (2018)

The decay of $]^{119}$Cd and $\^{119}$In isomers
por: Scheidemann, O, et al.
Publicado: (1976)

In Vivo Efficacy of HD0471953: A Novel GPR119 Agonist for the Treatment of Type 2 Diabetes Mellitus
por: Kim, So Ra, et al.
Publicado: (2013)

A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner
por: Miller, Sally, et al.
Publicado: (2017)

ZB-16, a Novel GPR119 Agonist, Relieves the Severity of Streptozotocin–Nicotinamide-Induced Diabetes in Rats
por: Tyurenkov, Ivan N., et al.
Publicado: (2017)

Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets
por: Ansarullah,, et al.
Publicado: (2016)

Targeting the GPR119/incretin axis: a promising new therapy for metabolic-associated fatty liver disease
por: Zhao, Jianan, et al.
Publicado: (2021)

Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice
por: McKillop, Aine M., et al.
Publicado: (2016)

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3
por: Zhao, Ye, et al.
Publicado: (2018)

High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice
por: Zhang, Meng, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8bf9hnrqfqr9h47g5b6uq03rrv