Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells

Cancer cells, including those of prostate cancer (PCa), often hijack intrinsic cell signaling to reprogram their metabolism. Part of this reprogramming includes the activation of de novo synthesis of fatty acids that not only serve as building blocks for membrane synthesis but also as energy sources...

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Detalles Bibliográficos
Autores principales: Liu, Shaoyou, Lai, Jiarun, Feng, Yuanfa, Zhuo, Yangjia, Zhang, Hui, Chen, Yupeng, Li, Jinchuang, Mei, Xinyue, Zeng, Yanting, Su, Jiaming, Deng, Yulin, Jiang, Funeng, Yang, Shengbang, Tan, Huijing, Hon, Chi Tin, Wei, Sun, Han, Zhaodong, Wang, Fen, Zhong, Weide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771725/
https://www.ncbi.nlm.nih.gov/pubmed/36410440
http://dx.doi.org/10.1016/j.jbc.2022.102720

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