Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron sub-lineages is reduced in convalescent sera regardless of infecting variant

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4 and BA.5 variants caused major waves of infections. Here, we assess the sensitivity of BA.4 to binding, neutralization, and antibody-dependent cellular cytotoxicity (ADCC) potential, measured by FcγRIIIa signaling, in conv...

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Detalles Bibliográficos
Autores principales: Richardson, Simone I., Kgagudi, Prudence, Manamela, Nelia P., Kaldine, Haajira, Venter, Elizabeth M., Pillay, Thanusha, Lambson, Bronwen E., van der Mescht, Mieke A., Hermanus, Tandile, Balla, Sashkia R., de Beer, Zelda, de Villiers, Talita R., Bodenstein, Annie, van den Berg, Gretha, du Pisanie, Marizane, Burgers, Wendy A., Ntusi, Ntobeko A.B., Abdullah, Fareed, Ueckermann, Veronica, Rossouw, Theresa M., Boswell, Michael T., Moore, Penny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771750/
https://www.ncbi.nlm.nih.gov/pubmed/36603577
http://dx.doi.org/10.1016/j.xcrm.2022.100910

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