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Crystal structure of Methanococcus jannaschii dihydroorotase

In this paper, we report the structural analysis of dihydroorotase (DHOase) from the hyperthermophilic and barophilic archaeon Methanococcus jannaschii. DHOase catalyzes the reversible cyclization of N‐carbamoyl‐l‐aspartate to l‐dihydroorotate in the third step of de novo pyrimidine biosynthesis. DH...

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Detalles Bibliográficos
Autores principales:	Vitali, Jacqueline, Nix, Jay C., Newman, Haley E., Colaneri, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9771888/ https://www.ncbi.nlm.nih.gov/pubmed/35978488 http://dx.doi.org/10.1002/prot.26412

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