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Potential role of serum hypoxia-inducible factor 1alpha as a biomarker of delayed cerebral ischemia and poor clinical outcome after human aneurysmal subarachnoid hemorrhage: A prospective, longitudinal, multicenter, and observational study

OBJECTIVE: Hypoxia-inducible factor 1alpha (HIF-1α) functions as a crucial transcriptional mediator in hypoxic and ischemic brain response. We endeavored to assess the prognostic significance of serum HIF-1α in human aneurysmal subarachnoid hemorrhage (aSAH). METHODS: In this prospective, longitudin...

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Detalles Bibliográficos
Autores principales: Cai, Ye-Yan, Zhuang, Yao-Kun, Wang, Wen-Jian, Jiang, Feng, Hu, Jie-Miao, Zhang, Xiao-Le, Zhang, Li-Xin, Lou, Xiao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772017/
https://www.ncbi.nlm.nih.gov/pubmed/36570456
http://dx.doi.org/10.3389/fneur.2022.1072351