The Single‐Component Flavin Reductase/Flavin‐Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins

Flavin‐dependent halogenases (FDHs) natively catalyze selective halogenation of electron rich aromatic and enolate groups. Nearly all FDHs reported to date require a separate flavin reductase to supply them with FADH(2), which complicates biocatalysis applications. In this study, we establish that t...

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Detalles Bibliográficos
Autores principales: Jiang, Yuhua, Snodgrass, Harrison M., Zubi, Yasmine S., Roof, Caitlin V., Guan, Yanfei, Mondal, Dibyendu, Honeycutt, Nicholas H., Lee, Johnny W., Lewis, Russell D., Martinez, Carlos A., Lewis, Jared C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772203/
https://www.ncbi.nlm.nih.gov/pubmed/36282507
http://dx.doi.org/10.1002/anie.202214610

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