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Structure of a RecT/Redβ family recombinase in complex with a duplex intermediate of DNA annealing

Some bacteriophage encode a recombinase that catalyzes single-stranded DNA annealing (SSA). These proteins are apparently related to RAD52, the primary human SSA protein. The best studied protein, Redβ from bacteriophage λ, binds weakly to ssDNA, not at all to dsDNA, but tightly to a duplex intermed...

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Detalles Bibliográficos
Autores principales: Caldwell, Brian J., Norris, Andrew S., Karbowski, Caroline F., Wiegand, Alyssa M., Wysocki, Vicki H., Bell, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772228/
https://www.ncbi.nlm.nih.gov/pubmed/36543802
http://dx.doi.org/10.1038/s41467-022-35572-z

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