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Tumor immune microenvironment and immunotherapy efficacy in BRAF mutation non-small-cell lung cancer

Previous small-size studies reported BRAF-mutated NSCLC patients have comparable sensitivity to immune checkpoint inhibitors (ICIs). However, how BRAF mutation affects the tumor immune microenvironment (TIME) is unknown. We performed Nanostring-panel RNA sequencing to evaluate TIME in 57 BRAF mutate...

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Detalles Bibliográficos
Autores principales: Li, Hui, Zhang, Yongchang, Xu, Yanjun, Huang, Zhiyu, Cheng, Guoping, Xie, Mingyin, Zhou, Zichao, Yu, Yangyang, Xi, Wenjing, Fan, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772302/
https://www.ncbi.nlm.nih.gov/pubmed/36543792
http://dx.doi.org/10.1038/s41419-022-05510-4

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