Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice

SUMOylation is a dynamic posttranslational modification, that provides fine-tuning of protein function involved in the cellular response to stress, differentiation, and tissue development. In the adrenal cortex, an emblematic endocrine organ that mediates adaptation to physiological demands, the SUM...

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Detalles Bibliográficos
Autores principales: Dufour, Damien, Dumontet, Typhanie, Sahut-Barnola, Isabelle, Carusi, Aude, Onzon, Méline, Pussard, Eric, Wilmouth, James Jr, Olabe, Julie, Lucas, Cécily, Levasseur, Adrien, Damon-Soubeyrand, Christelle, Pointud, Jean-Christophe, Roucher-Boulez, Florence, Tauveron, Igor, Bossis, Guillaume, Yeh, Edward T., Breault, David T., Val, Pierre, Lefrançois-Martinez, Anne-Marie, Martinez, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772323/
https://www.ncbi.nlm.nih.gov/pubmed/36543805
http://dx.doi.org/10.1038/s41467-022-35526-5

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