Cargando…

The deubiquitinase USP10 protects pancreatic cancer cells from endoplasmic reticulum stress

The ubiquitin-specific peptidase 10 (USP10) plays a context-specific, pro or anti-tumorigenic role in different malignancies. However, the role of USP10 in pancreatic cancer remains unclear. Our protein and RNA level analysis from archived specimens and public databases show that USP10 is overexpres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacharya, Udayan, Thavathiru, Elangovan, Neizer-Ashun, Fiifi, Xu, Chao, Gatalica, Zoran, Dwivedi, Shailendra Kumar Dhar, Dey, Anindya, Mukherjee, Priyabrata, Bhattacharya, Resham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772324/ https://www.ncbi.nlm.nih.gov/pubmed/36543867 http://dx.doi.org/10.1038/s41698-022-00336-x

Ejemplares similares

When the chains do not break: the role of USP10 in physiology and pathology
por: Bhattacharya, Udayan, et al.
Publicado: (2020)

KRCC1, a modulator of the DNA damage response
por: Neizer-Ashun, Fiifi, et al.
Publicado: (2022)

Targeting BMI1 mitigates chemoresistance in ovarian cancer
por: Dey, Anindya, et al.
Publicado: (2022)

A role for the cystathionine-β-synthase /H(2)S axis in astrocyte dysfunction in the aging brain
por: Dey, Anindya, et al.
Publicado: (2023)

Small Non-Coding-RNA in Gynecological Malignancies
por: Dwivedi, Shailendra Kumar Dhar, et al.
Publicado: (2021)

Targeting the TGFβ pathway in uterine carcinosarcoma
por: Dwivedi, Shailendra Kumar Dhar, et al.
Publicado: (2020)

Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2
por: Dey, Anindya, et al.
Publicado: (2020)

Bmi-1: At the crossroads of physiological and pathological biology
por: Bhattacharya, Resham, et al.
Publicado: (2015)

Corrigendum to ‘Bmi-1: At the crossroads of physiological and pathological biology’ [Genes & Diseases 2 (2015) 225–239]
por: Bhattacharya, Resham, et al.
Publicado: (2015)

BMI1, a new target of CK2α
por: Banerjee Mustafi, Soumyajit, et al.
Publicado: (2017)

Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer
por: Zhang, Xiaoqiang, et al.
Publicado: (2023)

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development in vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells
por: Zhang, Yushan, et al.
Publicado: (2020)

Role of TGF-β signaling in uterine carcinosarcoma
por: Dhar Dwivedi, Shailendra Kumar, et al.
Publicado: (2015)

Targeting deubiquitinase USP28 for cancer therapy
por: Wang, Xiaofang, et al.
Publicado: (2018)

Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth
por: Hossen, Md. Nazir, et al.
Publicado: (2022)

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
por: Palazón‐Riquelme, Pablo, et al.
Publicado: (2018)

Inhibition of the deubiquitinase USP10 induces degradation of SYK
por: Yang, Jing, et al.
Publicado: (2020)

Behavioral phenotyping of mice lacking the deubiquitinase USP2
por: Srikanta, Shashank Bangalore, et al.
Publicado: (2021)

Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*
por: Bhattacharya, Resham, et al.
Publicado: (2008)

USP48/USP31 Is a Nuclear Deubiquitinase that Potently Regulates Synapse Remodeling
por: Ma, Qi, et al.
Publicado: (2023)

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
por: Pérez-Mancera, Pedro A., et al.
Publicado: (2012)

Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas
por: Chinyengetere, Fadzai, et al.
Publicado: (2015)

Mechanism and regulation of the Lys6-selective deubiquitinase USP30
por: Gersch, Malte, et al.
Publicado: (2017)

The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases
por: Chou, Chon-Kit, et al.
Publicado: (2017)

The deubiquitinase USP11 is a versatile and conserved regulator of autophagy
por: Basic, Mila, et al.
Publicado: (2021)

Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30
por: Yan, Ding, et al.
Publicado: (2021)

Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
por: Toth, Rachel K., et al.
Publicado: (2022)

Targeting the deubiquitinase USP2 for malignant tumor therapy (Review)
por: Zhang, Shilong, et al.
Publicado: (2023)

Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer
por: Dhar Dwivedi, Shailendra Kumar, et al.
Publicado: (2016)

Gold Nanoparticles sensitize pancreatic cancer cells to gemcitabine
por: Huai, Yanyan, et al.
Publicado: (2019)

The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33
por: Ni, Yingmeng, et al.
Publicado: (2015)

Up‐regulated deubiquitinase USP4 plays an oncogenic role in melanoma
por: Guo, Weinan, et al.
Publicado: (2018)

The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth
por: Li, Wenjuan, et al.
Publicado: (2018)

Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy
por: Cui, Lang, et al.
Publicado: (2020)

The Mitochondrial Deubiquitinase USP30 Regulates AKT/mTOR Signaling
por: Zhang, Ruohan, et al.
Publicado: (2022)

The deubiquitinase USP11 promotes ovarian cancer chemoresistance by stabilizing BIP
por: Zhu, Xiaolin, et al.
Publicado: (2021)

USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
por: Campos-Iglesias, Diana, et al.
Publicado: (2023)

Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells
por: Francis, Meenal, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4mi5q395s6p23jad3sjgoeief5