Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies

INTRODUCTION: Imprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine immunogens. This approach, designated as a Non-Cognate Ligand Strategy (NCLS), has recently been used for the identification of p...

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Detalles Bibliográficos
Autores principales: Daniel Lišková, Veronika, Kosztyu, Petr, Kuchař, Milan, Černý, Jiří, Bharadwaj, Shiv, Petroková, Hana, Vroblová, Eliška, Křupka, Michal, Malý, Michal, Zosinčuková, Tereza, Šulc, Josef, Rašková Kafková, Leona, Raška, Milan, Malý, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772448/
https://www.ncbi.nlm.nih.gov/pubmed/36569830
http://dx.doi.org/10.3389/fimmu.2022.1066361

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