RUNX1 deficiency cooperates with SRSF2 mutation to induce multilineage hematopoietic defects characteristic of MDS

Myelodysplastic syndromes (MDSs) are a heterogeneous group of hematologic malignancies with a propensity to progress to acute myeloid leukemia. Causal mutations in multiple classes of genes have been identified in patients with MDS with some patients harboring more than 1 mutation. Interestingly, do...

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Detalles Bibliográficos
Autores principales: Huang, Yi-Jou, Chen, Jia-Yu, Yan, Ming, Davis, Amanda G., Miyauchi, Sayuri, Chen, Liang, Hao, Yajing, Katz, Sigrid, Bejar, Rafael, Abdel-Wahab, Omar, Fu, Xiang-Dong, Zhang, Dong-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772487/
https://www.ncbi.nlm.nih.gov/pubmed/36206200
http://dx.doi.org/10.1182/bloodadvances.2022007804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772487/
https://www.ncbi.nlm.nih.gov/pubmed/36206200
http://dx.doi.org/10.1182/bloodadvances.2022007804

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