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RUNX1 deficiency cooperates with SRSF2 mutation to induce multilineage hematopoietic defects characteristic of MDS
Myelodysplastic syndromes (MDSs) are a heterogeneous group of hematologic malignancies with a propensity to progress to acute myeloid leukemia. Causal mutations in multiple classes of genes have been identified in patients with MDS with some patients harboring more than 1 mutation. Interestingly, do...
Autores principales: | Huang, Yi-Jou, Chen, Jia-Yu, Yan, Ming, Davis, Amanda G., Miyauchi, Sayuri, Chen, Liang, Hao, Yajing, Katz, Sigrid, Bejar, Rafael, Abdel-Wahab, Omar, Fu, Xiang-Dong, Zhang, Dong-Er |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772487/ https://www.ncbi.nlm.nih.gov/pubmed/36206200 http://dx.doi.org/10.1182/bloodadvances.2022007804 |
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