Sex Differences in Genomic Features of Hepatitis B–Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity

BACKGROUND & AIMS: Aflatoxin exposure increases the risk for hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-infected individuals, particularly males. We investigated sex-based differences in the HCC genome and antitumor immunity. METHODS: Whole-genome, whole-exome, and RNA sequencing...

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Detalles Bibliográficos
Autores principales: Xu, Chungui, Cheng, Shaoyan, Chen, Kun, Song, Qianqian, Liu, Chang, Fan, Chunsun, Zhang, Ruochan, Zhu, Qing, Wu, Zhiyuan, Wang, Yuting, Fan, Jian, Zheng, Hongwei, Lu, Lingling, Chen, Taoyang, Zhao, Hong, Jiao, Yuchen, Qu, Chunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772570/
https://www.ncbi.nlm.nih.gov/pubmed/36272708
http://dx.doi.org/10.1016/j.jcmgh.2022.10.009

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