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Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China

BACKGROUND: The purpose of this paper is to study how the Delta variant spread in a China city, and to what extent the non-pharmaceutical prevention measures of local government be effective by reviewing the contact network of COVID-19 cases in Xi’an, China. METHODS: We organize the case reports of...

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Autores principales: Zhangbo, Yang, Zheng, Chen, Hui, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772588/
https://www.ncbi.nlm.nih.gov/pubmed/36550467
http://dx.doi.org/10.1186/s12889-022-14882-3
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author Zhangbo, Yang
Zheng, Chen
Hui, Wang
author_facet Zhangbo, Yang
Zheng, Chen
Hui, Wang
author_sort Zhangbo, Yang
collection PubMed
description BACKGROUND: The purpose of this paper is to study how the Delta variant spread in a China city, and to what extent the non-pharmaceutical prevention measures of local government be effective by reviewing the contact network of COVID-19 cases in Xi’an, China. METHODS: We organize the case reports of the Shaanxi Health Commission into a database by text coding and convert them into a network matrix. Then we construct a dynamic contact network for the corresponding analysis and calculate network indicators. we analyze the cases’ dynamic contact network structure and intervals between diagnosis time and isolation time by using data visualization, network analysis method, and Ordinary Least Square (OLS) regression. RESULTS: The contact network for this outbreak in Xi’an is very sparse, with a density of less than 0.0001. The contact network is a scale-free network. The average degree centrality is 0.741 and the average PageRank score is 0.0005. The network generated from a single source of infection contains 1371 components. We construct three variables of intervals and analyze the trend of intervals during the outbreak. The mean interval (interval 1) between case diagnosis time and isolation time is − 3.9 days. The mean of the interval (interval 2) between the infector’s diagnosis time and the infectee’s diagnosis time is 4.2 days. The mean of the interval (interval 3) between infector isolation time and infectee isolation time is 2.9 days. Among the three intervals, only interval 1 has a significant positive correlation with degree centrality. CONCLUSIONS: By integrating COVID-19 case reports of a Chinese city, we construct a contact network to analyze the dispersion of the outbreak. The network is a scale-free network with multiple hidden pathways that are not detected. The intervals of patients in this outbreak decreased compared to the beginning of the outbreak in 2020. City lockdown has a significant effect on the intervals that can affect patients’ network centrality. Our study highlights the value of case report text. By linking different reports, we can quickly analyze the spread of the epidemic in an urban area.
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spelling pubmed-97725882022-12-22 Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China Zhangbo, Yang Zheng, Chen Hui, Wang BMC Public Health Research BACKGROUND: The purpose of this paper is to study how the Delta variant spread in a China city, and to what extent the non-pharmaceutical prevention measures of local government be effective by reviewing the contact network of COVID-19 cases in Xi’an, China. METHODS: We organize the case reports of the Shaanxi Health Commission into a database by text coding and convert them into a network matrix. Then we construct a dynamic contact network for the corresponding analysis and calculate network indicators. we analyze the cases’ dynamic contact network structure and intervals between diagnosis time and isolation time by using data visualization, network analysis method, and Ordinary Least Square (OLS) regression. RESULTS: The contact network for this outbreak in Xi’an is very sparse, with a density of less than 0.0001. The contact network is a scale-free network. The average degree centrality is 0.741 and the average PageRank score is 0.0005. The network generated from a single source of infection contains 1371 components. We construct three variables of intervals and analyze the trend of intervals during the outbreak. The mean interval (interval 1) between case diagnosis time and isolation time is − 3.9 days. The mean of the interval (interval 2) between the infector’s diagnosis time and the infectee’s diagnosis time is 4.2 days. The mean of the interval (interval 3) between infector isolation time and infectee isolation time is 2.9 days. Among the three intervals, only interval 1 has a significant positive correlation with degree centrality. CONCLUSIONS: By integrating COVID-19 case reports of a Chinese city, we construct a contact network to analyze the dispersion of the outbreak. The network is a scale-free network with multiple hidden pathways that are not detected. The intervals of patients in this outbreak decreased compared to the beginning of the outbreak in 2020. City lockdown has a significant effect on the intervals that can affect patients’ network centrality. Our study highlights the value of case report text. By linking different reports, we can quickly analyze the spread of the epidemic in an urban area. BioMed Central 2022-12-22 /pmc/articles/PMC9772588/ /pubmed/36550467 http://dx.doi.org/10.1186/s12889-022-14882-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhangbo, Yang
Zheng, Chen
Hui, Wang
Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title_full Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title_fullStr Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title_full_unstemmed Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title_short Contact network analysis of COVID-19 Delta variant outbreak in urban China —based on 2,050 confirmed cases in Xi’an, China
title_sort contact network analysis of covid-19 delta variant outbreak in urban china —based on 2,050 confirmed cases in xi’an, china
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772588/
https://www.ncbi.nlm.nih.gov/pubmed/36550467
http://dx.doi.org/10.1186/s12889-022-14882-3
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