Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments

Tuberculosis (TB) is one of the main causes of death from a single pathological agent, Mycobacterium tuberculosis (Mtb). In addition, the emergence of drug-resistant TB strains has exacerbated even further the treatment outcome of TB patients. It is thus needed the search for new therapeutic strateg...

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Detalles Bibliográficos
Autores principales: Freitas de Freitas, Talita, Roth, Candida Deves, Abbadi, Bruno Lopes, Hopf, Fernanda Souza Macchi, Perelló, Marcia Alberton, de Matos Czeczot, Alexia, de Souza, Eduardo Vieira, Borsoi, Ana Flávia, Machado, Pablo, Bizarro, Cristiano Valim, Basso, Luiz Augusto, Timmers, Luis Fernando Saraiva Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772590/
https://www.ncbi.nlm.nih.gov/pubmed/36547753
http://dx.doi.org/10.1007/s10822-022-00495-w

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