Activated B cells suppress T-cell function through metabolic competition

BACKGROUND: B cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression are not fully understood. METHODS: We investigated...

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Detalles Bibliográficos
Autores principales: Imahashi, Nobuhiko, Basar, Rafet, Huang, Yuefan, Wang, Fang, Baran, Natalia, Banerjee, Pinaki Prosad, Lu, Junjun, Nunez Cortes, Ana Karen, Uprety, Nadima, Ensley, Emily, Muniz-Feliciano, Luis, Laskowski, Tamara J, Moyes, Judy S, Daher, May, Mendt, Mayela, Kerbauy, Lucila N, Shanley, Mayra, Li, Li, Lim, Francesca Lorraine Wei Inng, Shaim, Hila, Li, Ye, Konopleva, Marina, Green, Michael, Wargo, Jennifer, Shpall, Elizabeth J, Chen, Ken, Rezvani, Katayoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772692/
https://www.ncbi.nlm.nih.gov/pubmed/36543374
http://dx.doi.org/10.1136/jitc-2022-005644

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