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Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy

BACKGROUND: Glycogen synthase kinase 3β (GSK3β) was originally discovered to regulate glycogen synthesis and show a relationship to tumors. However, the biological functions of GSK3β in tumor-associated macrophages (TAMs) in cancers including hepatocellular carcinoma (HCC) remain unclear. METHODS: T...

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Detalles Bibliográficos
Autores principales:	Sun, Guangshun, Liu, Hanyuan, Zhao, Jie, Zhang, Jinyu, Huang, Tian, Sun, Guoqiang, Zhao, Siqi, Zhang, Zihao, Cao, Hengsong, Rong, Dawei, Kong, Xiangyi, Ji, Qinghua, Liu, Li, Wang, Xuehao, Tang, Weiwei, Xia, Yongxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772694/ https://www.ncbi.nlm.nih.gov/pubmed/36600662 http://dx.doi.org/10.1136/jitc-2022-005655

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