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Validation of a quantitative multiplex LC-MS/MS assay of carvedilol, enalaprilat, and perindoprilat in dried blood spots from heart failure patients and its cross validation with a plasma assay

INTRODUCTION: Adherence to medication is an important determinant of outcomes in chronic diseases like heart failure. Drug assays provide objective adherence biomarkers. Dried blood spots (DBS) are appealing samples for drug assays due to less demanding transportation and storage requirements. OBJEC...

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Detalles Bibliográficos
Autores principales:	Joubert, Andre, Joubert, Anton, van der Merwe, Marthinus, Norman, Jennifer, Castel, Sandra, Denti, Paolo, Sliwa, Karen, Maartens, Gary, Sinxadi, Phumla, Wiesner, Lubbe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772843/ https://www.ncbi.nlm.nih.gov/pubmed/36568714 http://dx.doi.org/10.1016/j.jmsacl.2022.12.003

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