Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report

Bictegravir (BIC) is included in international guidelines as the first line of therapy for patients living with Human Immunodeficiency Virus (HIV), either as initial therapy or as a replacement for patients with prior antiretroviral therapy (ART). Due to limited efficacy and safety data, BIC is curr...

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Detalles Bibliográficos
Autores principales: Alsulami, Shaimaa, Alotaibi, Sultan N., Damfu, Nader, Aljefri, Doaa M., Altayib, Hadeel Ahmed, Alharbi, Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772963/
https://www.ncbi.nlm.nih.gov/pubmed/36529886
http://dx.doi.org/10.1177/23259582221146110
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author Alsulami, Shaimaa
Alotaibi, Sultan N.
Damfu, Nader
Aljefri, Doaa M.
Altayib, Hadeel Ahmed
Alharbi, Maher
author_facet Alsulami, Shaimaa
Alotaibi, Sultan N.
Damfu, Nader
Aljefri, Doaa M.
Altayib, Hadeel Ahmed
Alharbi, Maher
author_sort Alsulami, Shaimaa
collection PubMed
description Bictegravir (BIC) is included in international guidelines as the first line of therapy for patients living with Human Immunodeficiency Virus (HIV), either as initial therapy or as a replacement for patients with prior antiretroviral therapy (ART). Due to limited efficacy and safety data, BIC is currently not recommended during pregnancy. Data on the safety and efficacy of BIC during pregnancy were unavailable at the time of drug approval. In our case, BIC/TAF/FTC was effective in suppressing viral load (VL) in pregnancy, and there were no reported safety issues for the mother or the baby.
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spelling pubmed-97729632022-12-23 Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report Alsulami, Shaimaa Alotaibi, Sultan N. Damfu, Nader Aljefri, Doaa M. Altayib, Hadeel Ahmed Alharbi, Maher J Int Assoc Provid AIDS Care Case Report Bictegravir (BIC) is included in international guidelines as the first line of therapy for patients living with Human Immunodeficiency Virus (HIV), either as initial therapy or as a replacement for patients with prior antiretroviral therapy (ART). Due to limited efficacy and safety data, BIC is currently not recommended during pregnancy. Data on the safety and efficacy of BIC during pregnancy were unavailable at the time of drug approval. In our case, BIC/TAF/FTC was effective in suppressing viral load (VL) in pregnancy, and there were no reported safety issues for the mother or the baby. SAGE Publications 2022-12-18 /pmc/articles/PMC9772963/ /pubmed/36529886 http://dx.doi.org/10.1177/23259582221146110 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Alsulami, Shaimaa
Alotaibi, Sultan N.
Damfu, Nader
Aljefri, Doaa M.
Altayib, Hadeel Ahmed
Alharbi, Maher
Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title_full Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title_fullStr Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title_full_unstemmed Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title_short Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report
title_sort efficacy and safety of bictegravir-based regimen in pregnant women living with hiv: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772963/
https://www.ncbi.nlm.nih.gov/pubmed/36529886
http://dx.doi.org/10.1177/23259582221146110
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