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The autonomic nervous system: A potential link to the efficacy of acupuncture

The autonomic nervous system (ANS) is a diffuse network that regulates physiological systems to maintain body homeostasis by integrating inputs from the internal and external environment, including the sympathetic, parasympathetic, and enteric nervous systems (ENS). Recent evidence suggests that ANS...

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Autores principales: Li, Yan-Wei, Li, Wei, Wang, Song-Tao, Gong, Yi-Nan, Dou, Bao-Min, Lyu, Zhong-Xi, Ulloa, Luis, Wang, Shen-Jun, Xu, Zhi-Fang, Guo, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772996/
https://www.ncbi.nlm.nih.gov/pubmed/36570846
http://dx.doi.org/10.3389/fnins.2022.1038945
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author Li, Yan-Wei
Li, Wei
Wang, Song-Tao
Gong, Yi-Nan
Dou, Bao-Min
Lyu, Zhong-Xi
Ulloa, Luis
Wang, Shen-Jun
Xu, Zhi-Fang
Guo, Yi
author_facet Li, Yan-Wei
Li, Wei
Wang, Song-Tao
Gong, Yi-Nan
Dou, Bao-Min
Lyu, Zhong-Xi
Ulloa, Luis
Wang, Shen-Jun
Xu, Zhi-Fang
Guo, Yi
author_sort Li, Yan-Wei
collection PubMed
description The autonomic nervous system (ANS) is a diffuse network that regulates physiological systems to maintain body homeostasis by integrating inputs from the internal and external environment, including the sympathetic, parasympathetic, and enteric nervous systems (ENS). Recent evidence suggests that ANS is one of the key neural pathways for acupuncture signal transduction, which has attracted worldwide attention in the acupuncture field. Here, we reviewed the basic and clinical research published in PubMed over the past 20 years on the effects of acupuncture on ANS regulation and homeostasis maintenance. It was found that acupuncture effectively alleviates ANS dysfunction-associated symptoms in its indications, such as migraine, depression, insomnia, functional dyspepsia, functional constipation. Acupuncture stimulation on some specific acupoints activates sensory nerve fibers, the spinal cord, and the brain. Using information integration and efferents from a complex network of autonomic nuclei of the brain, such as the insular cortex (IC), prefrontal cortex, anterior cingulate cortex (ACC), amygdala (AMG), hypothalamus, periaqueductal gray (PAG), nucleus tractus solitarius (NTS), ventrolateral medulla (VLM), nucleus ambiguus (AMB), acupuncture alleviates visceral dysfunction, inflammation via efferent autonomic nerves, and relieves pain and pain affect. The modulating pattern of sympathetic and parasympathetic nerves is associated with acupuncture stimulation on specific acupoints, intervention parameters, and disease models, and the relationships among them require further exploration. In conclusion, ANS is one of the therapeutic targets for acupuncture and mediates acupuncture’s actions, which restores homeostasis. A systemic study is needed to determine the rules and mechanisms underlying the effects of acupoint stimulation on corresponding organs mediated by specific central nervous networks and the efferent ANS.
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spelling pubmed-97729962022-12-23 The autonomic nervous system: A potential link to the efficacy of acupuncture Li, Yan-Wei Li, Wei Wang, Song-Tao Gong, Yi-Nan Dou, Bao-Min Lyu, Zhong-Xi Ulloa, Luis Wang, Shen-Jun Xu, Zhi-Fang Guo, Yi Front Neurosci Neuroscience The autonomic nervous system (ANS) is a diffuse network that regulates physiological systems to maintain body homeostasis by integrating inputs from the internal and external environment, including the sympathetic, parasympathetic, and enteric nervous systems (ENS). Recent evidence suggests that ANS is one of the key neural pathways for acupuncture signal transduction, which has attracted worldwide attention in the acupuncture field. Here, we reviewed the basic and clinical research published in PubMed over the past 20 years on the effects of acupuncture on ANS regulation and homeostasis maintenance. It was found that acupuncture effectively alleviates ANS dysfunction-associated symptoms in its indications, such as migraine, depression, insomnia, functional dyspepsia, functional constipation. Acupuncture stimulation on some specific acupoints activates sensory nerve fibers, the spinal cord, and the brain. Using information integration and efferents from a complex network of autonomic nuclei of the brain, such as the insular cortex (IC), prefrontal cortex, anterior cingulate cortex (ACC), amygdala (AMG), hypothalamus, periaqueductal gray (PAG), nucleus tractus solitarius (NTS), ventrolateral medulla (VLM), nucleus ambiguus (AMB), acupuncture alleviates visceral dysfunction, inflammation via efferent autonomic nerves, and relieves pain and pain affect. The modulating pattern of sympathetic and parasympathetic nerves is associated with acupuncture stimulation on specific acupoints, intervention parameters, and disease models, and the relationships among them require further exploration. In conclusion, ANS is one of the therapeutic targets for acupuncture and mediates acupuncture’s actions, which restores homeostasis. A systemic study is needed to determine the rules and mechanisms underlying the effects of acupoint stimulation on corresponding organs mediated by specific central nervous networks and the efferent ANS. Frontiers Media S.A. 2022-12-08 /pmc/articles/PMC9772996/ /pubmed/36570846 http://dx.doi.org/10.3389/fnins.2022.1038945 Text en Copyright © 2022 Li, Li, Wang, Gong, Dou, Lyu, Ulloa, Wang, Xu and Guo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Li, Yan-Wei
Li, Wei
Wang, Song-Tao
Gong, Yi-Nan
Dou, Bao-Min
Lyu, Zhong-Xi
Ulloa, Luis
Wang, Shen-Jun
Xu, Zhi-Fang
Guo, Yi
The autonomic nervous system: A potential link to the efficacy of acupuncture
title The autonomic nervous system: A potential link to the efficacy of acupuncture
title_full The autonomic nervous system: A potential link to the efficacy of acupuncture
title_fullStr The autonomic nervous system: A potential link to the efficacy of acupuncture
title_full_unstemmed The autonomic nervous system: A potential link to the efficacy of acupuncture
title_short The autonomic nervous system: A potential link to the efficacy of acupuncture
title_sort autonomic nervous system: a potential link to the efficacy of acupuncture
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772996/
https://www.ncbi.nlm.nih.gov/pubmed/36570846
http://dx.doi.org/10.3389/fnins.2022.1038945
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