Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia

For acute leukemia (AL) with adverse prognostic factors, allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the standard care option after the first complete remission. Meanwhile, as the success of haploidentical HSCT (haplo-HSCT), haploidentical donors (HIDs) become a reliable choice...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Wenshuai, Wu, Yamei, Guan, Lixun, Cheng, Longcan, Hu, Yalei, Tan, Min, Yang, Yuhui, Ning, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773128/
https://www.ncbi.nlm.nih.gov/pubmed/36568184
http://dx.doi.org/10.3389/fonc.2022.986144
_version_ 1784855131581317120
author Zheng, Wenshuai
Wu, Yamei
Guan, Lixun
Cheng, Longcan
Hu, Yalei
Tan, Min
Yang, Yuhui
Ning, Hongmei
author_facet Zheng, Wenshuai
Wu, Yamei
Guan, Lixun
Cheng, Longcan
Hu, Yalei
Tan, Min
Yang, Yuhui
Ning, Hongmei
author_sort Zheng, Wenshuai
collection PubMed
description For acute leukemia (AL) with adverse prognostic factors, allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the standard care option after the first complete remission. Meanwhile, as the success of haploidentical HSCT (haplo-HSCT), haploidentical donors (HIDs) become a reliable choice. However, there have been no reports on haplo-HSCT from HIDs with mild alpha(α)-thalassemia for AL yet. In the present report, we first describe two cases of successful haplo-HSCT from HIDs with mild α-thalassemia for AL.
format Online
Article
Text
id pubmed-9773128
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-97731282022-12-23 Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia Zheng, Wenshuai Wu, Yamei Guan, Lixun Cheng, Longcan Hu, Yalei Tan, Min Yang, Yuhui Ning, Hongmei Front Oncol Oncology For acute leukemia (AL) with adverse prognostic factors, allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the standard care option after the first complete remission. Meanwhile, as the success of haploidentical HSCT (haplo-HSCT), haploidentical donors (HIDs) become a reliable choice. However, there have been no reports on haplo-HSCT from HIDs with mild alpha(α)-thalassemia for AL yet. In the present report, we first describe two cases of successful haplo-HSCT from HIDs with mild α-thalassemia for AL. Frontiers Media S.A. 2022-12-08 /pmc/articles/PMC9773128/ /pubmed/36568184 http://dx.doi.org/10.3389/fonc.2022.986144 Text en Copyright © 2022 Zheng, Wu, Guan, Cheng, Hu, Tan, Yang and Ning https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zheng, Wenshuai
Wu, Yamei
Guan, Lixun
Cheng, Longcan
Hu, Yalei
Tan, Min
Yang, Yuhui
Ning, Hongmei
Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title_full Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title_fullStr Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title_full_unstemmed Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title_short Case report: First report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
title_sort case report: first report of haploidentical allogeneic hematopoietic stem cell transplantation from donors with mild alpha-thalassemia for acute leukemia
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773128/
https://www.ncbi.nlm.nih.gov/pubmed/36568184
http://dx.doi.org/10.3389/fonc.2022.986144
work_keys_str_mv AT zhengwenshuai casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT wuyamei casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT guanlixun casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT chenglongcan casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT huyalei casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT tanmin casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT yangyuhui casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia
AT ninghongmei casereportfirstreportofhaploidenticalallogeneichematopoieticstemcelltransplantationfromdonorswithmildalphathalassemiaforacuteleukemia

Ejemplares similares