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Hybrid Silver(I)-Doped Soybean Oil and Potato Starch Biopolymer Films to Combat Bacterial Biofilms
[Image: see text] This study describes the preparation, characterization, and antimicrobial properties of novel hybrid biopolymer materials doped with bioactive silver(I) coordination polymers (bioCPs). Two new bioCPs, [Ag(2)(μ(6)-hfa)](n) (1) and [Ag(2)(μ(4)-nda)(H(2)O)(2)](n) (2), were assembled f...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773233/ https://www.ncbi.nlm.nih.gov/pubmed/35621184 http://dx.doi.org/10.1021/acsami.2c03010 |
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author | Fernandes, Tiago A. Costa, Inês F.M. Jorge, Paula Sousa, Ana Catarina André, Vânia Cabral, Rafaela G. Cerca, Nuno Kirillov, Alexander M. |
author_facet | Fernandes, Tiago A. Costa, Inês F.M. Jorge, Paula Sousa, Ana Catarina André, Vânia Cabral, Rafaela G. Cerca, Nuno Kirillov, Alexander M. |
author_sort | Fernandes, Tiago A. |
collection | PubMed |
description | [Image: see text] This study describes the preparation, characterization, and antimicrobial properties of novel hybrid biopolymer materials doped with bioactive silver(I) coordination polymers (bioCPs). Two new bioCPs, [Ag(2)(μ(6)-hfa)](n) (1) and [Ag(2)(μ(4)-nda)(H(2)O)(2)](n) (2), were assembled from Ag(2)O and homophthalic (H(2)hfa) or 2,6-naphthalenedicarboxylic (H(2)nda) acids as unexplored building blocks. Their structures feature 2D metal–organic and supramolecular networks with 3,6L64 or sql topology. Both compounds act as active antimicrobial agents for producing bioCP-doped biopolymer films based on epoxidized soybean oil acrylate (SBO) or potato starch (PS) as model biopolymer materials with a different rate of degradability and silver release. BioCPs and their hybrid biopolymer films (1@[SBO](n), 2@[SBO](n), 1@[PS](n), and 2@[PS](n)) with a very low loading of coordination polymer (0.05–0.5 wt %) show remarkable antimicrobial activity against Staphylococcus aureus and Staphylococcus epidermidis (Gram-positive) and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacteria. Biopolymer films also effectively impair the formation of bacterial biofilms, allowing total biofilm inhibition in several cases. By reporting on new bioCPs and biopolymer films obtained from renewable biofeedstocks (soybean oil and PS), this study blends highly important research directions and widens a limited antimicrobial application of bioCPs and derived functional materials. This research thus opens up the perspectives for designing hybrid biopolymer films with outstanding bioactivity against bacterial biofilms. |
format | Online Article Text |
id | pubmed-9773233 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-97732332022-12-23 Hybrid Silver(I)-Doped Soybean Oil and Potato Starch Biopolymer Films to Combat Bacterial Biofilms Fernandes, Tiago A. Costa, Inês F.M. Jorge, Paula Sousa, Ana Catarina André, Vânia Cabral, Rafaela G. Cerca, Nuno Kirillov, Alexander M. ACS Appl Mater Interfaces [Image: see text] This study describes the preparation, characterization, and antimicrobial properties of novel hybrid biopolymer materials doped with bioactive silver(I) coordination polymers (bioCPs). Two new bioCPs, [Ag(2)(μ(6)-hfa)](n) (1) and [Ag(2)(μ(4)-nda)(H(2)O)(2)](n) (2), were assembled from Ag(2)O and homophthalic (H(2)hfa) or 2,6-naphthalenedicarboxylic (H(2)nda) acids as unexplored building blocks. Their structures feature 2D metal–organic and supramolecular networks with 3,6L64 or sql topology. Both compounds act as active antimicrobial agents for producing bioCP-doped biopolymer films based on epoxidized soybean oil acrylate (SBO) or potato starch (PS) as model biopolymer materials with a different rate of degradability and silver release. BioCPs and their hybrid biopolymer films (1@[SBO](n), 2@[SBO](n), 1@[PS](n), and 2@[PS](n)) with a very low loading of coordination polymer (0.05–0.5 wt %) show remarkable antimicrobial activity against Staphylococcus aureus and Staphylococcus epidermidis (Gram-positive) and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacteria. Biopolymer films also effectively impair the formation of bacterial biofilms, allowing total biofilm inhibition in several cases. By reporting on new bioCPs and biopolymer films obtained from renewable biofeedstocks (soybean oil and PS), this study blends highly important research directions and widens a limited antimicrobial application of bioCPs and derived functional materials. This research thus opens up the perspectives for designing hybrid biopolymer films with outstanding bioactivity against bacterial biofilms. American Chemical Society 2022-05-27 2022-06-08 /pmc/articles/PMC9773233/ /pubmed/35621184 http://dx.doi.org/10.1021/acsami.2c03010 Text en © 2022 American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Fernandes, Tiago A. Costa, Inês F.M. Jorge, Paula Sousa, Ana Catarina André, Vânia Cabral, Rafaela G. Cerca, Nuno Kirillov, Alexander M. Hybrid Silver(I)-Doped Soybean Oil and Potato Starch Biopolymer Films to Combat Bacterial Biofilms |
title | Hybrid
Silver(I)-Doped Soybean Oil and Potato Starch
Biopolymer Films to Combat Bacterial Biofilms |
title_full | Hybrid
Silver(I)-Doped Soybean Oil and Potato Starch
Biopolymer Films to Combat Bacterial Biofilms |
title_fullStr | Hybrid
Silver(I)-Doped Soybean Oil and Potato Starch
Biopolymer Films to Combat Bacterial Biofilms |
title_full_unstemmed | Hybrid
Silver(I)-Doped Soybean Oil and Potato Starch
Biopolymer Films to Combat Bacterial Biofilms |
title_short | Hybrid
Silver(I)-Doped Soybean Oil and Potato Starch
Biopolymer Films to Combat Bacterial Biofilms |
title_sort | hybrid
silver(i)-doped soybean oil and potato starch
biopolymer films to combat bacterial biofilms |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773233/ https://www.ncbi.nlm.nih.gov/pubmed/35621184 http://dx.doi.org/10.1021/acsami.2c03010 |
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