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Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically bett...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773284/ https://www.ncbi.nlm.nih.gov/pubmed/36347323 http://dx.doi.org/10.1016/j.ihj.2022.10.193 |
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author | Dash, Debabrata Mody, Rohit Ahmed, Naveed Malan, Sugandhna Reno Mody, Bhavya |
author_facet | Dash, Debabrata Mody, Rohit Ahmed, Naveed Malan, Sugandhna Reno Mody, Bhavya |
author_sort | Dash, Debabrata |
collection | PubMed |
description | When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically better results have been demonstrated. In most of the bifurcation lesions, the provisional technique of implanting a single stent in the main branch (MB) remains the default approach. However, some cases require more complex two-stent techniques which carry the risk of side branch (SB) restenosis. The concept of leaving no permanent implant behind is appealing because of the complexity of bifurcation anatomy with significant size mismatch between proximal and distal MB which may drive rates of in-stent restenosis and the potential impact of MB stenting affecting SB coronary flow dynamics. With the perspective of leaving lower metallic burden, a drug-coated balloon (DCB) has been utilized to treat bifurcations in both the MB and SB. The author gives an overview of the existing state of knowledge and prospects for the future for using DCB to treat bifurcation lesions. |
format | Online Article Text |
id | pubmed-9773284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-97732842022-12-23 Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? Dash, Debabrata Mody, Rohit Ahmed, Naveed Malan, Sugandhna Reno Mody, Bhavya Indian Heart J Review Article When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically better results have been demonstrated. In most of the bifurcation lesions, the provisional technique of implanting a single stent in the main branch (MB) remains the default approach. However, some cases require more complex two-stent techniques which carry the risk of side branch (SB) restenosis. The concept of leaving no permanent implant behind is appealing because of the complexity of bifurcation anatomy with significant size mismatch between proximal and distal MB which may drive rates of in-stent restenosis and the potential impact of MB stenting affecting SB coronary flow dynamics. With the perspective of leaving lower metallic burden, a drug-coated balloon (DCB) has been utilized to treat bifurcations in both the MB and SB. The author gives an overview of the existing state of knowledge and prospects for the future for using DCB to treat bifurcation lesions. Elsevier 2022 2022-11-05 /pmc/articles/PMC9773284/ /pubmed/36347323 http://dx.doi.org/10.1016/j.ihj.2022.10.193 Text en © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Dash, Debabrata Mody, Rohit Ahmed, Naveed Malan, Sugandhna Reno Mody, Bhavya Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title | Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title_full | Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title_fullStr | Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title_full_unstemmed | Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title_short | Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? |
title_sort | drug-coated balloon in the treatment of coronary bifurcation lesions: a hope or hype? |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773284/ https://www.ncbi.nlm.nih.gov/pubmed/36347323 http://dx.doi.org/10.1016/j.ihj.2022.10.193 |
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