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Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?

When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically bett...

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Autores principales: Dash, Debabrata, Mody, Rohit, Ahmed, Naveed, Malan, Sugandhna Reno, Mody, Bhavya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773284/
https://www.ncbi.nlm.nih.gov/pubmed/36347323
http://dx.doi.org/10.1016/j.ihj.2022.10.193
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author Dash, Debabrata
Mody, Rohit
Ahmed, Naveed
Malan, Sugandhna Reno
Mody, Bhavya
author_facet Dash, Debabrata
Mody, Rohit
Ahmed, Naveed
Malan, Sugandhna Reno
Mody, Bhavya
author_sort Dash, Debabrata
collection PubMed
description When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically better results have been demonstrated. In most of the bifurcation lesions, the provisional technique of implanting a single stent in the main branch (MB) remains the default approach. However, some cases require more complex two-stent techniques which carry the risk of side branch (SB) restenosis. The concept of leaving no permanent implant behind is appealing because of the complexity of bifurcation anatomy with significant size mismatch between proximal and distal MB which may drive rates of in-stent restenosis and the potential impact of MB stenting affecting SB coronary flow dynamics. With the perspective of leaving lower metallic burden, a drug-coated balloon (DCB) has been utilized to treat bifurcations in both the MB and SB. The author gives an overview of the existing state of knowledge and prospects for the future for using DCB to treat bifurcation lesions.
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spelling pubmed-97732842022-12-23 Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype? Dash, Debabrata Mody, Rohit Ahmed, Naveed Malan, Sugandhna Reno Mody, Bhavya Indian Heart J Review Article When compared to non-bifurcation lesions, percutaneous coronary intervention in coronary bifurcation lesions is technically demanding and has historically been limited by lower procedural success rates and inferior clinical results. Following the development of drug-eluting stents, dramatically better results have been demonstrated. In most of the bifurcation lesions, the provisional technique of implanting a single stent in the main branch (MB) remains the default approach. However, some cases require more complex two-stent techniques which carry the risk of side branch (SB) restenosis. The concept of leaving no permanent implant behind is appealing because of the complexity of bifurcation anatomy with significant size mismatch between proximal and distal MB which may drive rates of in-stent restenosis and the potential impact of MB stenting affecting SB coronary flow dynamics. With the perspective of leaving lower metallic burden, a drug-coated balloon (DCB) has been utilized to treat bifurcations in both the MB and SB. The author gives an overview of the existing state of knowledge and prospects for the future for using DCB to treat bifurcation lesions. Elsevier 2022 2022-11-05 /pmc/articles/PMC9773284/ /pubmed/36347323 http://dx.doi.org/10.1016/j.ihj.2022.10.193 Text en © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Dash, Debabrata
Mody, Rohit
Ahmed, Naveed
Malan, Sugandhna Reno
Mody, Bhavya
Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title_full Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title_fullStr Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title_full_unstemmed Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title_short Drug-coated balloon in the treatment of coronary bifurcation lesions: A hope or hype?
title_sort drug-coated balloon in the treatment of coronary bifurcation lesions: a hope or hype?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773284/
https://www.ncbi.nlm.nih.gov/pubmed/36347323
http://dx.doi.org/10.1016/j.ihj.2022.10.193
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