β-Lactamase Suppression as a Strategy to Target Methicillin-Resistant Staphylococcus aureus: Proof of Concept

[Image: see text] β-Lactamase (penicillinase) renders early, natural β-lactams like penicillin G useless against methicillin-resistant Staphylococcus aureus (MRSA), which also expresses PBP2a, responsible for resistance to semisynthetic, penicillinase-insensitive β-lactams like oxacillin. Antimicrob...

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Detalles Bibliográficos
Autores principales: Thomas, Payton M., Deming, Margaret A., Sarkar, Aurijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773349/
https://www.ncbi.nlm.nih.gov/pubmed/36570253
http://dx.doi.org/10.1021/acsomega.2c04381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773349/
https://www.ncbi.nlm.nih.gov/pubmed/36570253
http://dx.doi.org/10.1021/acsomega.2c04381

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