Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease

Human middle temporal gyrus (MTG) is a vulnerable brain region in early Alzheimer’s disease (AD), but little is known about the molecular mechanisms underlying this regional vulnerability. Here we utilize the 10 × Visium platform to define the spatial transcriptomic profile in both AD and control (C...

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Detalles Bibliográficos
Autores principales: Chen, Shuo, Chang, Yuzhou, Li, Liangping, Acosta, Diana, Li, Yang, Guo, Qi, Wang, Cankun, Turkes, Emir, Morrison, Cody, Julian, Dominic, Hester, Mark E., Scharre, Douglas W., Santiskulvong, Chintda, Song, Sarah XueYing, Plummer, Jasmine T., Serrano, Geidy E., Beach, Thomas G., Duff, Karen E., Ma, Qin, Fu, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773466/
https://www.ncbi.nlm.nih.gov/pubmed/36544231
http://dx.doi.org/10.1186/s40478-022-01494-6

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