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Molecular dissection of Janus kinases as drug targets for inflammatory diseases
The Janus kinase (JAK) family enzymes are non-receptor tyrosine kinases that phosphorylate cytokine receptors and signal transducer and activator of transcription (STAT) proteins in the JAK-STAT signaling pathway. Considering that JAK-STAT signal transduction is initiated by the binding of ligands,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773558/ https://www.ncbi.nlm.nih.gov/pubmed/36569926 http://dx.doi.org/10.3389/fimmu.2022.1075192 |