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The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients
STUDY OBJECTIVE: The coronavirus disease 2019 (COVID-19) outbreak has caused a severe burden on medical professionals, as the rapid disposition of patients is important. Therefore, we aimed to develop a new clinical assessment tool based on the shock index (SI) and age-shock index (ASI). We proposed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773782/ https://www.ncbi.nlm.nih.gov/pubmed/36586224 http://dx.doi.org/10.1016/j.ajem.2022.12.034 |
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author | Hsieh, Chien-Chieh Liu, Chia-yu Tsai, Kuang-Chau Jaw, Fu-Shan Chen, Jiashan |
author_facet | Hsieh, Chien-Chieh Liu, Chia-yu Tsai, Kuang-Chau Jaw, Fu-Shan Chen, Jiashan |
author_sort | Hsieh, Chien-Chieh |
collection | PubMed |
description | STUDY OBJECTIVE: The coronavirus disease 2019 (COVID-19) outbreak has caused a severe burden on medical professionals, as the rapid disposition of patients is important. Therefore, we aimed to develop a new clinical assessment tool based on the shock index (SI) and age-shock index (ASI). We proposed the hypoxia-age-shock index (HASI) and determined the usability of triage for COVID-19 infected patients in the first scene. METHODS: The predictive power for three indexes on mortality, intensive care unit (ICU) admission, and endotracheal intubation rate was evaluated using the receiver operating curve (ROC). We used DeLong's method for comparing the ROCs. RESULTS: The area under the curve (AUC) for ROC on mortality for SI, ASI, and HASI were 0.546, 0.771, and 0.773, respectively. The AUC on ICU admission mortality for SI, ASI, and HASI were 0.581, 0.700, and 0.743, respectively. The AUC for intubation for SI, ASI, and HASI were 0.592, 0.708, and 0.757, respectively. The AUC differences between HASI and SI showed statistically significant (P = 0.001) results on mortality, ICU admission, and intubation. Additionally, statistically significant results were found for the AUC difference between the HASI and ASI on ICU admission and intubation (P = 0.001 and P = 0.004, respectively). CONCLUSION: HASI can provide a better prediction compared to ASI on ICU admission and endotracheal intubation. HASI was more sensitive in mortality, ICU admission, and intubation prediction than the ASI. |
format | Online Article Text |
id | pubmed-9773782 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97737822022-12-22 The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients Hsieh, Chien-Chieh Liu, Chia-yu Tsai, Kuang-Chau Jaw, Fu-Shan Chen, Jiashan Am J Emerg Med Article STUDY OBJECTIVE: The coronavirus disease 2019 (COVID-19) outbreak has caused a severe burden on medical professionals, as the rapid disposition of patients is important. Therefore, we aimed to develop a new clinical assessment tool based on the shock index (SI) and age-shock index (ASI). We proposed the hypoxia-age-shock index (HASI) and determined the usability of triage for COVID-19 infected patients in the first scene. METHODS: The predictive power for three indexes on mortality, intensive care unit (ICU) admission, and endotracheal intubation rate was evaluated using the receiver operating curve (ROC). We used DeLong's method for comparing the ROCs. RESULTS: The area under the curve (AUC) for ROC on mortality for SI, ASI, and HASI were 0.546, 0.771, and 0.773, respectively. The AUC on ICU admission mortality for SI, ASI, and HASI were 0.581, 0.700, and 0.743, respectively. The AUC for intubation for SI, ASI, and HASI were 0.592, 0.708, and 0.757, respectively. The AUC differences between HASI and SI showed statistically significant (P = 0.001) results on mortality, ICU admission, and intubation. Additionally, statistically significant results were found for the AUC difference between the HASI and ASI on ICU admission and intubation (P = 0.001 and P = 0.004, respectively). CONCLUSION: HASI can provide a better prediction compared to ASI on ICU admission and endotracheal intubation. HASI was more sensitive in mortality, ICU admission, and intubation prediction than the ASI. Elsevier Inc. 2023-03 2022-12-22 /pmc/articles/PMC9773782/ /pubmed/36586224 http://dx.doi.org/10.1016/j.ajem.2022.12.034 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hsieh, Chien-Chieh Liu, Chia-yu Tsai, Kuang-Chau Jaw, Fu-Shan Chen, Jiashan The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title | The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title_full | The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title_fullStr | The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title_full_unstemmed | The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title_short | The hypoxia-age-shock index at triage to predict the outcomes of Covid-19 patients |
title_sort | hypoxia-age-shock index at triage to predict the outcomes of covid-19 patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773782/ https://www.ncbi.nlm.nih.gov/pubmed/36586224 http://dx.doi.org/10.1016/j.ajem.2022.12.034 |
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