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Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products

[Image: see text] Two polysaccharides were separately extracted and purified from different types of medicinal slices of Massa Medicata Fermentata (Sheng Massa Medicata Fermentata and Chao Massa Medicata Fermentata). The physicochemical properties of these polysaccharides were studied, including the...

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Autores principales: Liu, Shuang, Chen, Long, Duan, Wenjuan, Meng, Zhaoqing, Dong, Hongjing, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773791/
https://www.ncbi.nlm.nih.gov/pubmed/36570240
http://dx.doi.org/10.1021/acsomega.2c05932
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author Liu, Shuang
Chen, Long
Duan, Wenjuan
Meng, Zhaoqing
Dong, Hongjing
Wang, Xiao
author_facet Liu, Shuang
Chen, Long
Duan, Wenjuan
Meng, Zhaoqing
Dong, Hongjing
Wang, Xiao
author_sort Liu, Shuang
collection PubMed
description [Image: see text] Two polysaccharides were separately extracted and purified from different types of medicinal slices of Massa Medicata Fermentata (Sheng Massa Medicata Fermentata and Chao Massa Medicata Fermentata). The physicochemical properties of these polysaccharides were studied, including the molecular weight, monosaccharide composition, and glycosidic linkage. Moreover, inhibition of trypsin, α-amylase, and α-glucosidase by the polysaccharides and their antioxidant activity were investigated. Compared with polysaccharides from Sheng Massa Medicata Fermentata, polysaccharides from Chao Massa Medicata Fermentata had a lower molecular weight, higher uronic acid content, and a lower proportion of side chains. Polysaccharides from Sheng Massa Medicata Fermentata displayed stronger trypsin, α-amylase, and α-glucosidase inhibition activity, whereas the antioxidant activity of the polysaccharides from Chao Massa Medicata Fermentata was higher. These results indicated that stir-frying changes the physicochemical properties of the polysaccharides significantly, leading to reduced enzyme inhibition activity and an increase in antioxidant activity. This research provides a guide for the selective application of Massa Medicata Fermentata.
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spelling pubmed-97737912022-12-23 Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products Liu, Shuang Chen, Long Duan, Wenjuan Meng, Zhaoqing Dong, Hongjing Wang, Xiao ACS Omega [Image: see text] Two polysaccharides were separately extracted and purified from different types of medicinal slices of Massa Medicata Fermentata (Sheng Massa Medicata Fermentata and Chao Massa Medicata Fermentata). The physicochemical properties of these polysaccharides were studied, including the molecular weight, monosaccharide composition, and glycosidic linkage. Moreover, inhibition of trypsin, α-amylase, and α-glucosidase by the polysaccharides and their antioxidant activity were investigated. Compared with polysaccharides from Sheng Massa Medicata Fermentata, polysaccharides from Chao Massa Medicata Fermentata had a lower molecular weight, higher uronic acid content, and a lower proportion of side chains. Polysaccharides from Sheng Massa Medicata Fermentata displayed stronger trypsin, α-amylase, and α-glucosidase inhibition activity, whereas the antioxidant activity of the polysaccharides from Chao Massa Medicata Fermentata was higher. These results indicated that stir-frying changes the physicochemical properties of the polysaccharides significantly, leading to reduced enzyme inhibition activity and an increase in antioxidant activity. This research provides a guide for the selective application of Massa Medicata Fermentata. American Chemical Society 2022-12-07 /pmc/articles/PMC9773791/ /pubmed/36570240 http://dx.doi.org/10.1021/acsomega.2c05932 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Liu, Shuang
Chen, Long
Duan, Wenjuan
Meng, Zhaoqing
Dong, Hongjing
Wang, Xiao
Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title_full Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title_fullStr Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title_full_unstemmed Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title_short Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products
title_sort comparison of physicochemical and bioactive properties of polysaccharides from massa medicata fermentata and its processed products
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773791/
https://www.ncbi.nlm.nih.gov/pubmed/36570240
http://dx.doi.org/10.1021/acsomega.2c05932
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