Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one

[Image: see text] Herein, we report practical Cu(BF(4))(2)/activated carbon-catalyzed amination of various anilines, isoquinolinone, and naphthyridinone with aryl boronic acids. The ultrasonic and rotary evaporation treatment of the mixture of aq. Cu(BF(4))(2) and activated carbon in methanol afford...

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Autores principales: Wu, Shuang, Liu, Qiong, Zhang, Quanfeng, Zhou, Ya, Liu, Meiyan, Zeng, Youlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773803/
https://www.ncbi.nlm.nih.gov/pubmed/36570313
http://dx.doi.org/10.1021/acsomega.2c04299
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author Wu, Shuang
Liu, Qiong
Zhang, Quanfeng
Zhou, Ya
Liu, Meiyan
Zeng, Youlin
author_facet Wu, Shuang
Liu, Qiong
Zhang, Quanfeng
Zhou, Ya
Liu, Meiyan
Zeng, Youlin
author_sort Wu, Shuang
collection PubMed
description [Image: see text] Herein, we report practical Cu(BF(4))(2)/activated carbon-catalyzed amination of various anilines, isoquinolinone, and naphthyridinone with aryl boronic acids. The ultrasonic and rotary evaporation treatment of the mixture of aq. Cu(BF(4))(2) and activated carbon in methanol afforded a novel Cu(II)-catalyst, which is air-stable and can be effectively applied in the Chan–Lam coupling reaction. The products of N-arylation were isolated in good to excellent yields at low catalytic loading. And Cu(BF(4))(2)/AC also showed good reusability.
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spelling pubmed-97738032022-12-23 Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one Wu, Shuang Liu, Qiong Zhang, Quanfeng Zhou, Ya Liu, Meiyan Zeng, Youlin ACS Omega [Image: see text] Herein, we report practical Cu(BF(4))(2)/activated carbon-catalyzed amination of various anilines, isoquinolinone, and naphthyridinone with aryl boronic acids. The ultrasonic and rotary evaporation treatment of the mixture of aq. Cu(BF(4))(2) and activated carbon in methanol afforded a novel Cu(II)-catalyst, which is air-stable and can be effectively applied in the Chan–Lam coupling reaction. The products of N-arylation were isolated in good to excellent yields at low catalytic loading. And Cu(BF(4))(2)/AC also showed good reusability. American Chemical Society 2022-12-07 /pmc/articles/PMC9773803/ /pubmed/36570313 http://dx.doi.org/10.1021/acsomega.2c04299 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Wu, Shuang
Liu, Qiong
Zhang, Quanfeng
Zhou, Ya
Liu, Meiyan
Zeng, Youlin
Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title_full Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title_fullStr Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title_full_unstemmed Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title_short Cu(BF(4))(2)/AC-Catalyzed Synthesis of N-Substituted Anilines, N-Substituted 1,6-Naphthyridin-5(6H)-one, and Isoquinolin-1(2H)-one
title_sort cu(bf(4))(2)/ac-catalyzed synthesis of n-substituted anilines, n-substituted 1,6-naphthyridin-5(6h)-one, and isoquinolin-1(2h)-one
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773803/
https://www.ncbi.nlm.nih.gov/pubmed/36570313
http://dx.doi.org/10.1021/acsomega.2c04299
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