Dupilumab improves clinical symptoms in children with Netherton syndrome by suppressing Th2-mediated inflammation

BACKGROUND: Netherton syndrome is a rare, life-threatening autosomal recessive genetic disorder with no effective treatment yet. Skin barrier dysfunction caused by SPINK5 gene mutations is a hallmark of the disease. Antigen penetration through the defective skin and nonspecific inflammation provide...

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Detalles Bibliográficos
Autores principales: Yan, Shi, Wu, Xuege, Jiang, Jinqiu, Yu, Shijuan, Fang, Xiao, Yang, Huan, Bai, Xiaoming, Wang, Hua, Luo, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773867/
https://www.ncbi.nlm.nih.gov/pubmed/36569942
http://dx.doi.org/10.3389/fimmu.2022.1054422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773867/
https://www.ncbi.nlm.nih.gov/pubmed/36569942
http://dx.doi.org/10.3389/fimmu.2022.1054422

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