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How GRAIL controls Treg function to maintain self-tolerance

Regulatory T cells (T(regs)) normally maintain self-tolerance. T(regs) recognize “self” such that when they are not working properly, such as in autoimmunity, the immune system can attack and destroy one’s own tissues. Current therapies for autoimmunity rely on relatively ineffective and too often t...

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Detalles Bibliográficos
Autores principales: Fathman, C. Garrison, Yip, Linda, Gómez-Martín, Diana, Yu, Mang, Seroogy, Christine M., Hurt, Clarence R., Lin, Jack T., Jenks, Jennifer A., Nadeau, Kari C., Soares, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773990/
https://www.ncbi.nlm.nih.gov/pubmed/36569931
http://dx.doi.org/10.3389/fimmu.2022.1046631