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How GRAIL controls Treg function to maintain self-tolerance
Regulatory T cells (T(regs)) normally maintain self-tolerance. T(regs) recognize “self” such that when they are not working properly, such as in autoimmunity, the immune system can attack and destroy one’s own tissues. Current therapies for autoimmunity rely on relatively ineffective and too often t...
Autores principales: | Fathman, C. Garrison, Yip, Linda, Gómez-Martín, Diana, Yu, Mang, Seroogy, Christine M., Hurt, Clarence R., Lin, Jack T., Jenks, Jennifer A., Nadeau, Kari C., Soares, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773990/ https://www.ncbi.nlm.nih.gov/pubmed/36569931 http://dx.doi.org/10.3389/fimmu.2022.1046631 |
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